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Gene Expression Data
Assay Details
Assay
Reference: J:117240 Netzel-Arnett S, et al., Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation. J Biol Chem. 2006 Nov 3;281(44):32941-5
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7779947
Gene symbol: St14
Gene name: suppression of tumorigenicity 14 (colon carcinoma)
Reporter: lacZ
Direct Detection
Results
Specimen 1A: postnatal day 7; St14Gt(RST485)Byg/St14+ (more )
Structure Level Pattern Image Note
TS28: interfollicular epidermis Present Regionally restricted 1A Expression was confined to the uppermost living layer/uppermost terminally differentiating layer.
Specimen 1C: postnatal day 7; St14Gt(RST485)Byg/St14+ (more )
Note: Double labeled: cyan - St14 reporter; brown - Prss8 (assay MGI:7779948).
Structure Level Pattern Image Note
TS28: interfollicular epidermis Present Regionally restricted 1C Expression was confined to the uppermost living layer/uppermost terminally differentiating layer, overlapped with that of Prss8/prostasin.
Specimen 1E: postnatal newborn; St14Gt(RST485)Byg/St14+ (more )
Note: Double labeled: cyan - St14 reporter; brown - Prss8 (assay MGI:7779948).
Structure Level Pattern Image Note
TS27: interfollicular epidermis Present Regionally restricted 1E Expression was confined to the uppermost living layer/uppermost terminally differentiating layer, overlapped with that of Prss8/prostasin.
Specimen 1F: embryonic day 14.5; St14Gt(RST485)Byg/St14+ (more )
Note: Double labeled: cyan - St14 reporter; brown - Prss8 (assay MGI:7779948).
Structure Level Pattern Image Note
TS22: epidermis Absent 1F
Specimen 1G: embryonic day 15.5; St14Gt(RST485)Byg/St14+ (more )
Note: Double labeled: cyan - St14 reporter; brown - Prss8 (assay MGI:7779948).
Structure Level Pattern Image Note
TS23: epidermis Absent 1G
Specimen 1H: embryonic day 16.5; St14Gt(RST485)Byg/St14+ (more )
Note: Double labeled: cyan - St14 reporter; brown - Prss8 (assay MGI:7779948).
Structure Level Pattern Image Note
TS24: epidermis Present 1H
Specimen 1I: embryonic day 16.5; St14Gt(RST485)Byg/St14+ (more )
Note: Double labeled: cyan - St14 reporter; brown - Krt14 (assay MGI:7779949).
Structure Cell Type Level Pattern Image Note
TS24: epidermis suprabasal layer suprabasal keratinocyte Present 1I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory