About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:42321 Shirayoshi Y, et al., Proto-oncogene of int-3, a mouse Notch homologue, is expressed in endothelial cells during early embryogenesis. Genes Cells. 1997 Mar;2(3):213-24
Assay type: RNA in situ
MGI Accession ID: MGI:7764850
Gene symbol: Notch4
Gene name: notch 4
Probe: Notch4 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 3A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: head mesenchyme Present 3A Expression in cephalic mesenchyme.
TS13: dorsal aorta Present Widespread 3A Expression in dorsal aorta throughout embryo body.
TS13: endocardial tube Present 3A Expression in endocardium.
TS13: yolk sac mesenchyme Absent 3A No expression in yolk sac mesoderm.

Specimen 3B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: blood vessel Present Regionally restricted 3B ExpressIon in anterior/posterior cardinal veins, intersegmental vessels and vessels in branchial arches.
TS15: endocardial lining Weak 3B Weak expression in endocardium.

Specimen 3C: embryonic day 10.5 (more )
Structure Cell Type Level Pattern Image Note
TS17: vascular plexus blood vessel endothelial cell Present Regionally restricted 3C Expression in endothelial cells forming capillary plexuses.
TS17: head blood vessel Strong 3C Blood vessels in head and heart became more intensely labeled.
TS17: heart blood vessel Strong 3C Blood vessels in head and heart became more intensely labeled.
TS17: limb bud Present 3C Expression detected in limb buds.

Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: dorsal aorta Present 4A
TS13: heart Present 4A
TS13: vitelline vein Present 4A

Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Present 4B Expression in heart, vitelline vein and dorsal aorta.

Specimen 4C: embryonic day 9.5 (more )
Structure Cell Type Level Pattern Image Note
TS15: anterior cardinal vein blood vessel endothelial cell Present 4C

Specimen 4D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: intersomitic blood vessel Present 4D
TS17: vascular plexus Present Regionally restricted 4D Expression in capillary plexuses.

Specimen E8.5 not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: allantois Present Expression in allantois and allantoic stalk.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory