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Gene Expression Data
Assay Details
Assay
Reference: J:173598 Jacquet BV, et al., Specification of a Foxj1-Dependent Lineage in the Forebrain Is Required for Embryonic-to-Postnatal Transition of Neurogenesis in the Olfactory Bulb. J Neurosci. 2011 Jun 22;31(25):9368-82
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7764095
Gene symbol: Calb2
Gene name: calbindin 2
Antibody: anti-calretinin
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2B +/+: postnatal day 21 (more )
Note: Double labeled: green - Calb2; red - Nissl.
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 2B +/+ CR
TS28: main olfactory bulb layer Present 2B +/+ CR
Specimen 2B -/-: postnatal day 21; Foxj1tm1Slb/Foxj1tm1Slb (more )
Note: Double labeled: green - Calb2; red - Nissl.
Structure Level Pattern Image Note
TS28: main olfactory bulb layer Present Regionally restricted 2B -/- CR Massive depletion of positive neurons and nearly absence of the glomerular layer were seen.
Specimen 2D Dnaic-/-: postnatal day 21; Dnai1tm1.2Leo/Dnai1tm1.2Leo (more )
Note: Double labeled: green - Calb2; red - Nissl.
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 2D -/- CR Similar as in the wild-type.
TS28: main olfactory bulb layer Present 2D -/- CR Similar as in the wild-type.
Specimen 2G +/+: postnatal day 6 (more )
Note: Double labeled: green - Calb2; red - Nissl.
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 2G +/+ CR
TS28: main olfactory bulb layer Present 2G +/+ CR
Specimen 2G -/-: postnatal day 6; Foxj1tm1Slb/Foxj1tm1Slb (more )
Note: Double labeled: green - Calb2; red - Nissl.
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Present 2G -/- CR Decreased expression and significantly smaller compared with the wild-type.
TS28: main olfactory bulb layer Present 2G -/- CR Decreased expression and significantly smaller compared with the wild-type.
Specimen 10A GL/EPL: postnatal day 21; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(FOXJ1-cre)F26Htzm/0 (more )
Note: Conditional mutant. Double labeled: green - Calb2; red - Cre reporter.
Structure Level Pattern Image Note
TS28: main olfactory bulb layer Present 10A left-5 Most of the cells did not coexpressed with tdTomato in the superficial layers.
Specimen 10B GL/EPL: postnatal day 90; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(FOXJ1-cre)F26Htzm/0 (more )
Note: Conditional mutant. Double labeled: green - Calb2; red - Cre reporter.
Structure Level Pattern Image Note
TS28: main olfactory bulb layer Present 10B-5 Most of the cells did not coexpressed with tdTomato in the superficial layers.
Specimen 10A ML/GCL: postnatal day 21; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(FOXJ1-cre)F26Htzm/0 (more )
Note: Conditional mutant. Double labeled: green - Calb2; red - Cre reporter.
Structure Level Pattern Image Note
TS28: main olfactory bulb layer Present 10A left-6 Some of the cells (<10%) coexpressed with tdTomato in the deep layers.
Specimen 10B ML/GCL: postnatal day 90; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Tg(FOXJ1-cre)F26Htzm/0 (more )
Note: Conditional mutant. Double labeled: green - Calb2; red - Cre reporter.
Structure Level Pattern Image Note
TS28: main olfactory bulb layer Present 10B-6 Some of the cells (<20%) coexpressed with tdTomato in the deep layers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory