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Gene Expression Data
Assay Details
Assay
Reference: J:108403 Kim SY, et al., The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation. J Neurosci. 2006 Apr 26;26(17):4567-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7748730
Gene symbol: Nr4a2
Gene name: nuclear receptor subfamily 4, group A, member 2
Antibody: anti-Nurr1 (M-196): sc-5568
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 2B E14 WT: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 2B E14 WT right , 2B E14 WT left Expression is in the ventral midbrain.
Specimen 2B E14 D2R-/-: embryonic day 14.5; Drd2tm1Ebo/Drd2tm1Ebo (more )
Structure Level Pattern Image Note
TS22: midbrain Weak Regionally restricted 2B E14 D2R-/- right , 2B E14 D2R-/- left The number of expressing cells was significantly reduced in the ventral midbrain (70% of WT mice).
Specimen 2B P30 WT: postnatal day 30 (more )
Structure Level Pattern Image Note
TS28: midbrain Present Regionally restricted 2B P30 WT left , 2B P30 WT right Expression is in the ventral midbrain.
Specimen 2B P30 D2R-/-: postnatal day 30; Drd2tm1Ebo/Drd2tm1Ebo (more )
Structure Level Pattern Image Note
TS28: midbrain Present Regionally restricted 2B P30 D2R-/- right , 2B P30 D2R-/- left The number of expressing cells was significantly reduced in the ventral midbrain (86% of WT mice).
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory