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Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7738434
Gene symbol: Nes
Gene name: nestin
Antibody: Anti-Nestin
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen S5A miR-9-2 +/+; miR9-3 +/+: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex radial glial cell Present Regionally restricted S5A Nestin top Expression was detected in radial glial cells.
Specimen S5A miR-9-2 -/-; miR9-3 -/-: embryonic day 12.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS20: cerebral cortex radial glial cell Present S5A Nestin bottom Nestin-positive radial glial cells were almost normal in the miR-9-2/3 double mutants.
Specimen S8E: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: telencephalon radial glial cell Present Regionally restricted S8E The pallial/subpallial boundary is marked morphologically by a fasciculated palisade of radial glial fibers.
Specimen S8F: embryonic day 14.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS22: telencephalon radial glial cell Present Regionally restricted S8F In miR-9-2/3 double mutants, the Nestin-positive glial palisade was aberrant and less fasciculated.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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