About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: RNA in situ
MGI Accession ID: MGI:7737660
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Probe: Isl1 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 9K: embryonic day 15.5 (more )
Structure Cell Type Level Pattern Image Note
TS23: corpus striatum striatum neuron Present Regionally restricted 9K Expression was detected in the differentiating field.
TS23: lateral ganglionic eminence Present Regionally restricted 9K Expression was detected in the lateral ganglionic eminence subventricular zone.

Specimen 9L: embryonic day 15.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS23: corpus striatum striatum neuron Weak Regionally restricted 9L Expression in the differentiating field was reduced in the double mutant.
TS23: lateral ganglionic eminence Present Regionally restricted 9L Expression in the lateral ganglionic eminence subventricular zone was markedly expanded.

Specimen 10E': embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon neuron of the forebrain Present Regionally restricted 10E' Expression was detected in corridor neurons between the Nkx2-1-positive proliferating zone and globus pallidus.

Specimen 10F': embryonic day 13.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Cell Type Level Pattern Image Note
TS21: telencephalon neuron of the forebrain Present Regionally restricted 10F' Isl1-positive corridor neurons were expanded or dispersed in the miR-9-2/3 double mutants.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory