Gene Expression Data
Assay Details
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Assay
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Reference:
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J:89119
Jones L, et al., Pax6 is required for the normal development of the forebrain axonal connections. Development. 2002 Nov;129(21):5041-52
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7736629
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Gene symbol:
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L1cam
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Gene name:
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L1 cell adhesion molecule
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Antibody:
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anti-L1
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
5A/B:
embryonic day 14.5
(more  )
Specimen
5A/B:
(close  )
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Genetic Background:
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involves: C57BL/6J * DBA/2J * NMRI
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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Specimen
5C/D:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cerebral hemisphere white matter |
Present |
Regionally restricted |
5D
,
5C
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Expression in thalamocortical axons and corticofugal axons that are aberrant; thalamic axons fail to extend towards cortex. Corticofugal axons fail to turn towards internal capsule.
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Specimen
5E/I:
embryonic day 18.5
(more )
Specimen
5E/I:
(close )
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Genetic Background:
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involves: C57BL/6J * DBA/2J * NMRI
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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Specimen
5F/J:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral hemisphere white matter |
Present |
Regionally restricted |
5F
,
5J
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Expression in fibers with trajectories following aberrant pathways, not crossing the pallial/subpallial boundary.
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Specimen
5G/K:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral hemisphere white matter |
Present |
Regionally restricted |
5K
,
5G
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Expression in fibers with trajectories following aberrant pathways, not crossing the pallial/subpallial boundary.
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Specimen
5H/L:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Agarose
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: cerebral cortex |
Present |
Regionally restricted |
5H
,
5L
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Expression in axons with abnormal fasciculation along dorsal cortex.
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Analysis Tools
