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Gene Expression Data
Assay Details
Assay
Reference: J:89119 Jones L, et al., Pax6 is required for the normal development of the forebrain axonal connections. Development. 2002 Nov;129(21):5041-52
Assay type: RNA in situ
MGI Accession ID: MGI:7736625
Gene symbol: Sema3c
Gene name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
Probe: Sema3c probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 8A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Present Regionally restricted 8A Expression in cortex confined to subventricular zone and intermediate zone of entire pallium, including dorsal, lateral and ventral pallial domains.
TS22: cerebral cortex subventricular zone Present Regionally restricted 8A Expression in cortex confined to subventricular zone and intermediate zone of entire pallium, including dorsal, lateral and ventral pallial domains.

Specimen 8B: embryonic day 14.5; Pax6tm1Pgr/Pax6+ (more )
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Present Regionally restricted 8B Expression in cortex similar to wild type.
TS22: cerebral cortex subventricular zone Present Regionally restricted 8B Expression in cortex similar to wild type.

Specimen 8C: embryonic day 14.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS22: pallium Present Regionally restricted 8C Expression completely abolished in region of ventral and lateral pallium.
TS22: cortical plate Present Regionally restricted 8C In dorsal pallium, expression shifted into most superfical zone of cortical plate.

Specimen E18.5 wild type not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: pallium Present Regionally restricted Expression fainter but still detectable all along extending corticofugal axons torards basolateral telencephalon.

Specimen E18.5 Pax6-/- not shown: embryonic day 18.5; Pax6tm1Pgr/Pax6tm1Pgr (more )
Structure Level Pattern Image Note
TS26: pallium Present Regionally restricted Expression not detectable within ventral and lateral pallium.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory