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Gene Expression Data
Assay Details
Assay
Reference: J:69569 DiPersio CM, et al., alpha3beta1 Integrin is required for normal development of the epidermal basement membrane. J Cell Biol. 1997 May 5;137(3):729-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736215
Gene symbol: Itga6
Gene name: integrin alpha 6
Antibody: anti-alpha6 integrin (GoH3)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to fluorescein
Results
Specimen 4A: postnatal newborn (more )
Note: Double labeled with Lama5 (assay MGI:7736211 ).
Structure Cell Type Level Pattern Image Note
TS27: epidermis basal layer keratinocyte Present Regionally restricted 4A , 4B Expression is concentrated at the basal surfaces of keratinocytes.
Specimen 4E: postnatal newborn; Itga3tm1Jak/Itga3tm1Jak (more )
Note: Double labeled with Lama5 (assay MGI:7736211 ).
Structure Cell Type Level Pattern Image Note
TS27: epidermis basal layer keratinocyte Present Regionally restricted 4E , 4F Expression is concentrated at the basal surfaces of keratinocytes.
Specimen 4I: postnatal newborn; Itga3tm1Jak/Itga3tm1Jak (more )
Note: Double labeled with Lama5 (assay MGI:7736211 ).
Structure Cell Type Level Pattern Image Note
TS27: basement membrane keratinocyte Present Regionally restricted 4I , 4J Expression is concentrated at the basal surfaces of keratinocytes on the epidermal sides of blisters.
TS27: epidermis basal layer keratinocyte Present Regionally restricted 4I , 4J Expression is concentrated at the basal surfaces of keratinocytes on the epidermal sides of blisters.
Specimen 7E: embryonic day 15.5; Itga3tm1Jak/Itga3tm1Jak (more )
Structure Level Pattern Image Note
TS23: basement membrane Present 7E In this mutant some staining is disorganized compared to wild-type.
Specimen 7I: embryonic day 17.5; Itga3tm1Jak/Itga3tm1Jak (more )
Structure Level Pattern Image Note
TS25: basement membrane Present 7I In this mutant staining is disorganized compared to wild-type.
Specimen 7K: embryonic day 17.5; Itga3tm1Jak/Itga3tm1Jak (more )
Structure Level Pattern Image Note
TS25: basement membrane Present 7K In this mutant staining is disorganized compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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