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Gene Expression Data
Assay Details
Assay
Reference: J:57046 Zhadanov AB, et al., Absence of the tight junctional protein AF-6 disrupts epithelial cell-cell junctions and cell polarity during mouse development. Curr Biol. 1999 Aug 26;9(16):880-8
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7734724
Gene symbol: Cdh1
Gene name: cadherin 1
Antibody: anti-E-cadherin
Assay notes: Two Afdn antibodies were described, but the one used in this assay was not detailed. Anti-AF-6 MGI:7734709 may have been used in this assay.
Results
Specimen 6b: embryonic day 7.5 (more )
Note: Double labeled: green - Cdh1; red - Afdn (assay MGI:7734722).
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 6b Expression overlapping with that of Afdn.
Specimen 7c: embryonic day 7.5 (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Present 7c
Specimen 7d: embryonic day 7.5; Afdntm1Mrcr/Afdntm1Mrcr (more )
Structure Level Pattern Image Note
TS11: neural ectoderm Present 7d Expression not significantly different compared to wild type.
Specimen 7e: embryonic day 7.5 (more )
Note: Double labeled: red - Cdh1; green - Prom1 (assay MGI:7734725).
Structure Level Pattern Image Note
TS11: neural ectoderm Present 7e Minimal overlap with Prom1 expression.
Specimen 7f: embryonic day 7.5; Afdntm1Mrcr/Afdntm1Mrcr (more )
Note: Double labeled: red - Cdh1; green - Prom1 (assay MGI:7734725).
Structure Level Pattern Image Note
TS11: neural ectoderm Present Regionally restricted 7f Significant basolateral colocalization with Prom1 expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory