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Gene Expression Data
Assay Details
Assay
Reference: J:170495 Ikeda K, et al., Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. Int J Dev Biol. 2010;54(10):1453-64
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7720113
Gene symbol: Six1
Gene name: sine oculis-related homeobox 1
Antibody: anti-Six1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2Aa/c/e: embryonic day 13.5 (more )
Note: Double labeled: green - Six1; red - Mki67 (assay MGI:7720114).
Structure Level Pattern Image Note
TS21: olfactory epithelium Present 2Aa , 2Ac , 2Ae Coexpressed with Mki67 in the apical and basal layers.

Specimen 2Ba/c/e: embryonic day 13.5 (more )
Note: Double labeled: green - Six1; red - Neurod1 (assay MGI:7720115).
Structure Level Pattern Image Note
TS21: olfactory epithelium Present Regionally restricted 2Bc , 2Ba , 2Be Expressed in the apical and basal layers. Coexpressed with Neurod1 in the basal layer cells.

Specimen 2Ca/c/e: embryonic day 13.5 (more )
Note: Double labeled: green - Six1; red - Hes1 (assay MGI:7720116).
Structure Level Pattern Image Note
TS21: olfactory epithelium Present Regionally restricted 2Cc , 2Ce , 2Ca Expressed in the apical and basal layers. Coexpressed with Hes1 in the apical cells.
TS21: nasal mesenchyme Moderate Regionally restricted 2Ca , 2Cc , 2Ce Moderate to low expression in the mesenchyme underlying the olfactory epithelium.

Specimen 2Da/c/e: embryonic day 16.5 (more )
Note: Double labeled: green - Six1; red - Neurod1 (assay MGI:7720115).
Structure Level Pattern Image Note
TS24: olfactory epithelium Present Regionally restricted 2Dc , 2De , 2Da Expressed in the apical and basal layers. Coexpressed with Neurod1 in the basal layer cells.

Specimen 2Ea/c/e: embryonic day 16.5 (more )
Note: Double labeled: green - Six1; red - Uchl1 (assay MGI:7720117).
Structure Level Pattern Image Note
TS24: olfactory epithelium Present Regionally restricted 2Ea , 2Ec , 2Ee Expressed in the apical and basal layers. Not coexpressed with Uchl1/PGP9.5.

Specimen 2Fa/c/e: embryonic day 16.5 (more )
Note: Double labeled: green - Six1; red - Omp (assay MGI:7720118).
Structure Level Pattern Image Note
TS24: olfactory epithelium Present Regionally restricted 2Fc , 2Fe , 2Fa Expressed in the apical and basal layers. Not coexpressed with Omp.

Specimen 2Ga/c/e: postnatal month 1.5 (more )
Note: Double labeled: green - Six1; red - SUS-4.
Structure Cell Type Level Pattern Image Note
TS28: olfactory epithelium olfactory epithelial supporting cell Present 2Ge , 2Ga , 2Gc Expressed in the nuclei. Supporting cells/sustentacular cells were marked by SUS-4.

Specimen 2Ha/c/e: postnatal month 1.5 (more )
Note: Double labeled: green - Six1; red - Mki67 (assay MGI:7720114).
Structure Cell Type Level Pattern Image Note
TS28: olfactory epithelium globose cell of olfactory epithelium Present 2He , 2Hc , 2Ha Coexpressed with Mki67.
TS28: olfactory epithelium olfactory epithelial supporting cell Present 2He , 2Hc , 2Ha Coexpressed with Mki67.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory