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Gene Expression Data
Assay Details
Assay
Reference: J:333283 Guan N, et al., Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency. Kidney Int. 2022 Jul;102(1):108-120
Assay type: RNA in situ
MGI Accession ID: MGI:7718717
Gene symbol: Uqcrq
Gene name: ubiquinol-cytochrome c reductase, complex III subunit VII
Probe: BA-Mm-Uqcrq-3zz-st
Probe preparation: Antisense RNA
Results
Specimen 3a Cre-: postnatal week 6; Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Double labeled: red - Uqcrq; brown - DBA.
Structure Level Pattern Image Note
TS28: collecting duct epithelium Present 3a Qpc left
Specimen 3a Hoxb7-Qpc-/-: postnatal week 6; Tg(Hoxb7-cre)13Amc/0, Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Conditional mutant. Double labeled: red - Uqcrq; brown - DBA.
Structure Level Pattern Image Note
TS28: collecting duct epithelium Present 3a Qpc right
Specimen S3 Cre-: embryonic day 16.5; Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Double labeled: red - Uqcrq; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS24: metanephros Present S3_merge left , S3_Qpc left
TS24: ureteric tip Present S3_merge left , S3_Qpc left
TS24: ureteric trunk Present S3_merge left , S3_Qpc left
Specimen S3 Hoxb7-Qpc-/-: embryonic day 16.5; Tg(Hoxb7-cre)13Amc/0, Uqcrqtm1.1Ncdl/Uqcrqtm1.1Ncdl (more )
Note: Conditional mutant. Double labeled: red - Uqcrq; green - pan-cytokeratin.
Structure Level Pattern Image Note
TS24: ureteric tip Absent S3_merge right , S3_Qpc right
TS24: ureteric trunk Absent S3_merge right , S3_Qpc right
TS24: metanephros Present Regionally restricted S3_Qpc right Expression in the ureteric tip and trunk was inactivated.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory