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Gene Expression Data
Assay Details
Assay
Reference: J:332292 Zhang Y, et al., Mutations in the TBX15-ADAMTS2 pathway associate with a novel soft palate dysplasia. Hum Mutat. 2022 Dec;43(12):2102-2115
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7717002
Gene symbol: Adamts2
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 2
Antibody: anti-ADAMTS2 (ab125226)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 5b1,b2,b3: embryonic day 13.5 (more )
Note: Double labeled: green - Adamts2; brown - Tbx15 (assay MGI:7717001).
Structure Level Pattern Image Note
TS21: secondary palate Present Regionally restricted 5b1 , 5d1 , 5b2 , 5b3 , 5d2 , 5d3 Expression in posterior palate co-localized with Tbx15 expression in posterior palatal mesenchymal cells.
Specimen 5b4,b5: embryonic day 15.5 (more )
Note: Double labeled: green - Adamts2; brown - Tbx15 (assay MGI:7717001).
Structure Level Pattern Image Note
TS23: secondary palate Present Regionally restricted 5d4 , 5b5 , 5b4 , 5d5 Expression in posterior palate co-localized with Adamts2 expression in fused palatal shelves at E15.5.
Specimen 5b6,b7: embryonic day 18.5 (more )
Note: Double labeled: green - Adamts2; brown - Tbx15 (assay MGI:7717001).
Structure Level Pattern Image Note
TS26: secondary palate Present 5b7 , 5d6 , 5d7 , 5b6 Expression in posterior palate.
Specimen 6a1,a2,a3: embryonic day 13.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS21: secondary palate Present Regionally restricted 6a2 , 6e2 , 6e3 , 6e1 , 6a1 , 6a3 Expression in middle palate.
Specimen 6a4,a5,a6: embryonic day 13.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS21: secondary palate Present 6e6 , 6e5 , 6a6 , 6e4 , 6a4 , 6a5 Expression in posterior palate.
Specimen S2a1,a2: embryonic day 15.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS23: secondary palate Present Regionally restricted S2e2 , S2a2 , S2a1 , S2e1 Expression in middle palate.
Specimen S2a3,a4: embryonic day 15.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS23: secondary palate Present S2a4 , S2a3 , S2e3 , S2e4 Expression in posterior palate.
Specimen S2a5,a6: embryonic day 18.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS26: secondary palate Present S2a6 , S2e6 , S2e5 , S2a5 Expression in middle palate.
Specimen S2a7,a8: embryonic day 18.5 (more )
Note: Triple labeled: green - Adamts2; red - Col1a1 (assay MGI:7717004); brown - Sox9 (assay MGI:7717003).
Structure Level Pattern Image Note
TS26: secondary palate Present S2e7 , S2a7 , S2e8 , S2a8 Expression in posterior palate.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory