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Gene Expression Data
Assay Details
Assay
Reference: J:350008 Karwacki-Neisius V, et al., WNT signalling control by KDM5C during development affects cognition. Nature. 2024 Mar;627(8004):594-603
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7714679
Gene symbol: Pax6
Gene name: paired box 6
Antibody: anti-Pax6 (#PRB-278P; #30130, #901301)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1f WT: embryonic day 13.5 (more )
Note: Double labeled: red - Pax6; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex forebrain radial glial cell Present 1f WT PAX6 Expression is seen in radial glial cells.

Specimen 1f KO: embryonic day 13.5; Kdm5ctm1.2Yshi/Y (more )
Note: Double labeled: red - Pax6; blue - Hoechst.
Structure Cell Type Level Pattern Image Note
TS21: cerebral cortex forebrain radial glial cell Present 1f KO PAX6 Expression is seen in radial glial cells; the numbers in the mutant are comparable to those seen in wild type. However, the subventricular zone and cortical plate are reduced in size.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory