Gene Expression Data
Assay Details
Assay
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Reference:
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J:244304
Richardson R, et al., p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017 Jun;13(6):e1006828
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7713315
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Gene symbol:
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Nectin4
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Gene name:
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nectin cell adhesion molecule 4
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Results
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Specimen
5I:
embryonic day 13.5
(more )
Specimen
5I:
(close )
Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS21: palatal shelf epithelium |
Strong |
Regionally restricted |
5I
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Expressed at the junction between the periderm/basal cells throughout the palatal epithelia.
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Specimen
5J:
embryonic day 13.5
(more )
Specimen
5J:
(close )
Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: palatal shelf epithelium |
Strong |
Regionally restricted |
5J
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Expressed at the junction between the periderm/basal cells in the palatal epithelia.
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Specimen
5K:
(close )
Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Mutant Allele(s):
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Trp63tm1Fmc/Trp63tm1Fmc
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Structure |
Level |
Pattern |
Image |
Note |
TS21: palatal shelf epithelium |
Strong |
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5K
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Expression levels were comparable to those of wild-type. Expression was mis-localized and was detected ectopically between adjacent basal cells.
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Specimen
5L:
(close )
Genetic Background:
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involves: 129S4/SvJae * BALB/c
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Mutant Allele(s):
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Trp63tm1Fmc/Trp63tm1Fmc
|
Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
|
4% Paraformaldehyde
|
Structure |
Level |
Pattern |
Image |
Note |
TS21: palatal shelf epithelium |
Strong |
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5L
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Expression levels were comparable to those of wild-type. Mis-localized in the epithelia was seen, expressed between adjacent basal cells.
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