About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:244304 Richardson R, et al., p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017 Jun;13(6):e1006828
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7713277
Gene symbol: Krt17
Gene name: keratin 17
Results
Specimen 1J: embryonic day 14.5 (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS22: palatal shelf epithelium peridermal cell Present 1J Positive periderm cells migrated out of the medial edge epithelia to form the oral and nasal epithelial triangles.
Specimen 1K: embryonic day 14.5; Tgfb3tm1Doe/Tgfb3tm1Doe (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS22: palatal shelf epithelium peridermal cell Present 1K Positive periderm layers persist and the palatal shelves fail to adhere/fuse.
Specimen 1L: embryonic day 14.5; Tgfb3tm1Doe/Tgfb3tm1Doe, Trp63tm1Fmc/Trp63+ (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS22: palatal shelf epithelium peridermal cell Present 1L Migration out of the medial edge epithelia to form the oral and nasal epithelial triangles was restored.
Specimen 4F: embryonic day 12.5 (more )
Structure Cell Type Level Pattern Image Note
TS20: palatal shelf epithelium peridermal cell Present Regionally restricted 4F Expressed in a number of flattened cells overlying the basal epithelia.
Specimen 4G: embryonic day 12.5; Trp63tm1Fmc/Trp63tm1Fmc (more )
Structure Level Pattern Image Note
TS20: palatal shelf epithelium Absent 4G
Specimen 4H: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium peridermal cell Present Widespread 4H Expressed throughout the periderm layer.
Specimen 4I: embryonic day 13.5; Trp63tm1Fmc/Trp63tm1Fmc (more )
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Present Patchy 4I Ectopic expression was detected in basal epithelial cells. The flattened cells were absent and individual `bead-like' positive cells were observed.
Specimen 6G: embryonic day 14.5 (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS22: palatal shelf epithelium peridermal cell Present 6G Positive periderm cells migrated out of the medial edge epithelia to form the oral and nasal epithelial triangles.
Specimen S1J: embryonic day 13.5 (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium peridermal cell Present S1J
Specimen S1K: embryonic day 13.5; Tgfb3tm1Doe/Tgfb3tm1Doe (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium peridermal cell Present S1K Similar as in the wild-type.
Specimen S1L: embryonic day 13.5; Tgfb3tm1Doe/Tgfb3tm1Doe, Trp63tm1Fmc/Trp63+ (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium peridermal cell Present S1L Similar as in the wild-type.
Specimen S5C: embryonic day 13.5 (more )
Note: Double labeled: green - Krt17; red - Krt14 (assay MGI:7713276).
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium peridermal cell Present S5C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory