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Gene Expression Data
Assay Details
Assay
Reference: J:244304 Richardson R, et al., p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017 Jun;13(6):e1006828
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7713275
Gene symbol: Cdh1
Gene name: cadherin 1
Results
Specimen 1G: embryonic day 14.5 (more )
Note: Double labeled: red - Cdh1; green - pH3.
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present 1G No proliferation (pH3+) in the medial edge epithelia.
Specimen 1H: embryonic day 14.5; Tgfb3tm1Doe/Tgfb3tm1Doe (more )
Note: Double labeled: red - Cdh1; green - pH3.
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present 1H
Specimen 1I: embryonic day 14.5; Tgfb3tm1Doe/Tgfb3tm1Doe, Trp63tm1Fmc/Trp63+ (more )
Note: Double labeled: red - Cdh1; green - pH3.
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present 1I No proliferation (pH3+) in the medial edge epithelia, as in the wild-type.
Specimen S1G: embryonic day 13.5 (more )
Note: Double labeled: red - Cdh1; green - pH3.
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Present S1G PH3+ proliferative cells were seen.
Specimen S1H: embryonic day 13.5; Tgfb3tm1Doe/Tgfb3tm1Doe (more )
Note: Double labeled: red - Cdh1; green - pH3.
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Present S1H PH3+ proliferative cells were seen, similar as in the wild-type.
Specimen S1I: embryonic day 13.5; Tgfb3tm1Doe/Tgfb3tm1Doe, Trp63tm1Fmc/Trp63+ (more )
Note: Double labeled: red - Cdh1; green - pH3.
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Present S1I PH3+ proliferative cells were seen, similar as in the wild-type.
Specimen S5E: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Present S5E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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