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Gene Expression Data
Assay Details
Assay
Reference: J:244304 Richardson R, et al., p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate. PLoS Genet. 2017 Jun;13(6):e1006828
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7713267
Gene symbol: Casp3
Gene name: caspase 3
Results
Specimen 1D: embryonic day 14.5 (more )
Note: Double labeled: green - Casp3; red - Trp63 (assay MGI:7713273).
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Single cells 1D Apoptotic activity in the oral and nasal epithelial triangles was seen.
Specimen 1E: embryonic day 14.5; Tgfb3tm1Doe/Tgfb3tm1Doe (more )
Note: Double labeled: green - Casp3; red - Trp63 (assay MGI:7713273).
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Absent 1E
Specimen 1F: embryonic day 14.5; Tgfb3tm1Doe/Tgfb3tm1Doe, Trp63tm1Fmc/Trp63+ (more )
Note: Double labeled: green - Casp3; red - Trp63 (assay MGI:7713273).
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Single cells 1F Apoptotic activity in the medial edge epithelia was restored.
Specimen 6E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: palatal shelf epithelium Present Single cells 6E Apoptotic activity in the oral and nasal epithelial triangles was seen.
Specimen S1D: embryonic day 13.5 (more )
Note: Double labeled: green - Casp3; red - Trp63 (assay MGI:7713273).
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Absent S1D
Specimen S1E: embryonic day 13.5; Tgfb3tm1Doe/Tgfb3tm1Doe (more )
Note: Double labeled: green - Casp3; red - Trp63 (assay MGI:7713273).
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Absent S1E
Specimen S1F: embryonic day 13.5; Tgfb3tm1Doe/Tgfb3tm1Doe, Trp63tm1Fmc/Trp63+ (more )
Note: Double labeled: green - Casp3; red - Trp63 (assay MGI:7713273).
Structure Cell Type Level Pattern Image Note
TS21: palatal shelf epithelium basal cell of epidermis Absent S1F
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory