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Gene Expression Data
Assay Details
Assay
Reference: J:123817 Chalasani SH, et al., The chemokine stromal cell-derived factor-1 promotes the survival of embryonic retinal ganglion cells. J Neurosci. 2003 Jun 1;23(11):4601-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7713208
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Results
Specimen 9A: embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: retina ganglion cell layer retinal ganglion cell Present 9A Expression is in retinal ganglion cells.
Specimen not shown E13.5 -/-: embryonic day 13.5; Cxcr4tm1Yzo/Cxcr4tm1Yzo (more )
Structure Cell Type Level Pattern Image Note
TS21: retina ganglion cell layer retinal ganglion cell Present There is an approximate 35% reduction in the numberof stained retinal ganglion cells in this mutant compared with wild-type littermates.
Specimen not shown E11.5 +/+: embryonic day 11.5 (more )
Structure Cell Type Level Pattern Image Note
TS19: neural retina retinal ganglion cell Present Regionally restricted Expression is in retinal ganglion cells.
Specimen not shown E11.5 -/-: embryonic day 11.5; Cxcr4tm1Yzo/Cxcr4tm1Yzo (more )
Structure Cell Type Level Pattern Image Note
TS19: neural retina retinal ganglion cell Present Regionally restricted Expression in this mutant is similar to wild-type and no differences in the number of neurons were seen between the mutant and wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory