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Gene Expression Data
Assay Details
Assay
Reference: J:85927 Lilliehook C, et al., Altered Abeta formation and long-term potentiation in a calsenilin knock-out. J Neurosci. 2003 Oct 8;23(27):9097-106
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7712024
Gene symbol: Kcnip3
Gene name: Kv channel interacting protein 3, calsenilin
Reporter: lacZ
Direct Detection
Results
Specimen 3A: embryonic day 14.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde.
Structure Level Pattern Image Note
TS22: midbrain Strong 3A
TS22: forebrain Present 3A
TS22: spinal cord Absent 3A
Specimen 3B: embryonic day 14.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS22: tectum Strong Regionally restricted 3B Expression is in the ventricular zone.
TS22: epithalamus Present 3B
Specimen 3C: embryonic day 15.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde.
Structure Level Pattern Image Note
TS23: midbrain Strong 3C
TS23: cerebral cortex ventricular layer Present 3C
TS23: hippocampus Present Regionally restricted 3C Expression is in the ventricular zone.
Specimen 3D: embryonic day 14.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS22: epithalamus Strong 3D
TS22: tectum Strong Regionally restricted 3D Expression is in a subpopulation.
TS22: cerebral cortex ventricular layer Present 3D
Specimen 3E: embryonic day 18.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde.
Structure Level Pattern Image Note
TS26: midbrain Strong 3E
Specimen 3F: embryonic day 16.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS24: hippocampus Present Regionally restricted 3F Expression is in the ventricular zone.
Specimen 3G: embryonic day 16.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 3G
Specimen 3H: embryonic day 16.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS24: inferior colliculus Present 3H
Specimen 4A: postnatal day 4; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 4A
TS28: midbrain Present 4A
Specimen 4B: postnatal day 8; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong 4B
TS28: cerebellum granule cell layer Strong 4B
Specimen 4C: postnatal day 20; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present Graded 4C Expression is in an anteroposterior gradient.
TS28: cerebellum Purkinje cell layer Absent 4C
Specimen 4D: postnatal adult; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde.
Structure Level Pattern Image Note
TS28: cortical layer VI Strong 4D
TS28: dentate gyrus Strong 4D
TS28: piriform cortex Strong 4D
TS28: amygdala Weak 4D
TS28: hippocampus CA3 Weak 4D
TS28: visual cortex Weak Regionally restricted 4D Expression is in layer IV.
Specimen 4E: postnatal adult; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: subiculum Strong 4E
TS28: entorhinal cortex Strong Regionally restricted 4E Expression is in layer II.
Specimen 4F: postnatal adult; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: dentate gyrus Strong 4F
TS28: hippocampus granule cell layer Present 4F
Specimen not shown: embryonic day 12.0; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde.
Structure Level Pattern Image Note
TS20: embryo Present
Specimen Table 1: postnatal; Kcnip3tm1Bux/Kcnip3tm1Bux (more )
Note: Fixative was 2% formaldehyde with a postfix in 4% paraformaldehyde.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Very strong
TS28: cortical layer VI Very strong
TS28: dentate gyrus Very strong
TS28: piriform cortex Very strong
TS28: entorhinal cortex Strong
TS28: amygdala Weak
TS28: inferior colliculus Weak
TS28: visual cortex Weak Regionally restricted Expression is in layer IV.
TS28: basal ganglia Absent
TS28: cerebellum Purkinje cell layer Absent
TS28: cortical layer I Absent
TS28: cortical layer II Absent
TS28: cortical layer III Absent
TS28: cortical layer IV Absent
TS28: cortical layer V Absent
TS28: deep cerebellar nucleus Absent
TS28: habenula Absent
TS28: hippocampus CA1 Absent
TS28: hippocampus CA2 Absent
TS28: hippocampus CA3 Absent
TS28: main olfactory bulb Absent
TS28: substantia nigra Absent
TS28: superior colliculus Absent
TS28: thalamus Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory