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Gene Expression Data
Assay Details
Assay
Reference: J:321836 Zhao K, et al., LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development. Development. 2022 Mar 15;149(6):dev200458
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7711945
Gene symbol: Tnnt2
Gene name: troponin T2, cardiac
Antibody: Anti-Troponin T MS295P1 clone 13-11 (MA5-12960)
Detection system: Secondary antibody
Results
Specimen 2B Ctrl: embryonic day 9.5 (more )
Note: Double labeled: green - Tnnt2; red - Isl1 (assay MGI:7711943).
Structure Cell Type Level Pattern Image Note
TS15: cardiac muscle tissue fetal cardiomyocyte Present 2B Ctrl
Specimen 2B cKO: embryonic day 9.5; Lonp1tm1.1Zzy/Lonp1tm1.1Zzy, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - Isl1 (assay MGI:7711943).
Structure Cell Type Level Pattern Image Note
TS15: cardiac muscle tissue fetal cardiomyocyte Present 2B cKO
Specimen 4C Ctrl: embryonic day 12.5 (more )
Note: Double labeled: green - Tnnt2; red - Slc2a1 (assay MGI:7711984).
Structure Cell Type Level Pattern Image Note
TS20: ventricle cardiac muscle fetal cardiomyocyte Present 4C Ctrl merge , 4C Ctrl cTnt
Specimen 4C cKO: embryonic day 12.5; Lonp1tm1.1Zzy/Lonp1tm1.1Zzy, Tg(Tnnt2-cre)5Blh/0 (more )
Note: Conditional mutant. Double labeled: green - Tnnt2; red - Slc2a1 (assay MGI:7711984).
Structure Cell Type Level Pattern Image Note
TS20: ventricle cardiac muscle fetal cardiomyocyte Present 4C cKO cTnt , 4C cKO merge
Specimen S2 E10.5 proximal-distal Ctrl: embryonic day 10.5 (more )
Note: Triple labeled: green - Tnnt2; white - Pecam1 (assay MGI:7712249); red - Vim (assay MGI:7712248).
Structure Cell Type Level Pattern Image Note
TS17: outflow tract cardiac muscle cardiac muscle cell Present S2_E10.5 Ctrl-4 , S2_E10.5 Ctrl-2 , S2_E10.5 Ctrl-3 , S2_E10.5 Ctrl-1 , S2_E10.5 Ctrl-5
Specimen S2 E10.5 proximal-distal cKO: embryonic day 10.5; Lonp1tm1.1Zzy/Lonp1tm1.1Zzy, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Triple labeled: green - Tnnt2; white - Pecam1 (assay MGI:7712249); red - Vim (assay MGI:7712248).
Structure Cell Type Level Pattern Image Note
TS17: outflow tract cardiac muscle cardiac muscle cell Present S2_E10.5 cKO-2 , S2_E10.5 cKO-1 , S2_E10.5 cKO-3 , S2_E10.5 cKO-4 , S2_E10.5 cKO-5 Similar as in the control.
Specimen S2 E11.5 proximal-distal Ctrl: embryonic day 11.5 (more )
Note: Triple labeled: green - Tnnt2; white - Pecam1 (assay MGI:7712249); red - Vim (assay MGI:7712248).
Structure Cell Type Level Pattern Image Note
TS19: outflow tract cardiac muscle cardiac muscle cell Present S2_E11.5 Ctrl-4 , S2_E11.5 Ctrl-1 , S2_E11.5 Ctrl-5 , S2_E11.5 Ctrl-2 , S2_E11.5 Ctrl-3
Specimen S2 E11.5 proximal-distal cKO: embryonic day 11.5; Lonp1tm1.1Zzy/Lonp1tm1.1Zzy, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Triple labeled: green - Tnnt2; white - Pecam1 (assay MGI:7712249); red - Vim (assay MGI:7712248).
Structure Cell Type Level Pattern Image Note
TS19: outflow tract cardiac muscle cardiac muscle cell Present S2_E11.5 cKO-5 , S2_E11.5 cKO-3 , S2_E11.5 cKO-1 , S2_E11.5 cKO-2 , S2_E11.5 cKO-4 Similar as in the control.
Specimen S2 E12.5 proximal-distal Ctrl: embryonic day 12.5 (more )
Note: Triple labeled: green - Tnnt2; white - Pecam1 (assay MGI:7712249); red - Vim (assay MGI:7712248).
Structure Cell Type Level Pattern Image Note
TS20: outflow tract cardiac muscle cardiac muscle cell Present S2_E12.5 Ctrl-4 , S2_E12.5 Ctrl-5 , S2_E12.5 Ctrl-2 , S2_E12.5 Ctrl-3 , S2_E12.5 Ctrl-1
Specimen S2 E12.5 proximal-distal cKO: embryonic day 12.5; Lonp1tm1.1Zzy/Lonp1tm1.1Zzy, Tg(Mef2c-cre)2Blk/0 (more )
Note: Conditional mutant. Triple labeled: green - Tnnt2; white - Pecam1 (assay MGI:7712249); red - Vim (assay MGI:7712248).
Structure Cell Type Level Pattern Image Note
TS20: outflow tract cardiac muscle cardiac muscle cell Present S2_E12.5 cKO-1 , S2_E12.5 cKO-4 , S2_E12.5 cKO-3 , S2_E12.5 cKO-5 , S2_E12.5 cKO-2 Similar as in the control.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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