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Gene Expression Data
Assay Details
Assay
Reference: J:163793 McDonald LA, et al., Comparison of Iroquois gene expression in limbs/fins of vertebrate embryos. J Anat. 2010 Jun;216(6):683-91
Assay type: RNA in situ
MGI Accession ID: MGI:7709790
Gene symbol: Irx2
Gene name: Iroquois homeobox 2
Probe: IMAGE clone 5347048
Probe preparation: Antisense RNA
Results
Specimen 2/S2E fl: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted S2E fl , 2E fl Expressed in the proximal regions. Much weaker than that of Irx1.

Specimen 2/S2E hl: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted 2E hl , S2E hl Expressed in the proximal regions. Much weaker than that of Irx1.

Specimen 2/S2F fl: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb digit Present 2F fl , S2F fl Expression was stronger in the developing digit condensations.
TS20: forelimb digit 2 Present 2F fl , S2F fl Expression was seen first and was strongest.
TS20: forelimb digit 3 Present 2F fl , S2F fl Expression was seen first and was strongest.
TS20: forelimb digit 4 Present 2F fl , S2F fl Expression was seen first and was strongest.
TS20: forelimb digit 1 Present S2F fl , 2F fl Weaker expression.
TS20: forelimb digit 5 Present S2F fl , 2F fl Weaker expression.

Specimen 2/S2F hl: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb digit Present S2F hl , 2F hl Expression was stronger in the developing digit condensations.
TS20: hindlimb digit 2 Present 2F hl , S2F hl Expression was seen first and was strongest.
TS20: hindlimb digit 3 Present 2F hl , S2F hl Expression was seen first and was strongest.
TS20: hindlimb digit 4 Present 2F hl , S2F hl Expression was seen first and was strongest.
TS20: hindlimb digit 1 Present 2F hl , S2F hl Weaker expression.
TS20: hindlimb digit 5 Present 2F hl , S2F hl Weaker expression.

Specimen 2/S2G fl: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: forelimb digit 2 Present Regionally restricted S2G fl , 2G fl Expression was stronger in the joint-forming regions.
TS21: forelimb digit 3 Present Regionally restricted S2G fl , 2G fl Expression was stronger in the joint-forming regions.
TS21: forelimb digit 4 Present Regionally restricted S2G fl , 2G fl Expression was stronger in the joint-forming regions.
TS21: hand joint Present Regionally restricted S2G fl , 2G fl Expression was stronger in the digits 2, 3 and 4.

Specimen 2/S2G hl: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindlimb digit 2 Present Regionally restricted 2G hl , S2G hl Expression was stronger in the joint-forming regions.
TS21: hindlimb digit 3 Present Regionally restricted 2G hl , S2G hl Expression was stronger in the joint-forming regions.
TS21: hindlimb digit 4 Present Regionally restricted 2G hl , S2G hl Expression was stronger in the joint-forming regions.
TS21: foot joint Present Regionally restricted 2G hl , S2G hl Expression was stronger in the digits 2, 3 and 4.

Specimen 2/S2H fl: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hand joint Present Regionally restricted S2H fl , 2H fl Expressed in joint-forming regions in all digits.

Specimen 2/S2H hl: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: foot joint Present Regionally restricted 2H hl , S2H hl Expressed in joint-forming regions in all digits.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory