Th Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:54931 Finotto S, et al., Analysis of mice carrying targeted mutations of the glucocorticoid receptor gene argues against an essential role of glucocorticoid signalling for generating adrenal chromaffin cells. Development. 1999 Jul;126(13):2935-44
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7709674
Gene symbol:	Th
Gene name:	tyrosine hydroxylase

Antibody:	anti-tyrosine hydoxylase
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to Cy3

Results

Specimen E13.5 wt not shown: embryonic day 13.5 (more

)
Note: Additional data presented in Figs. 2 and 3.

Structure	Cell Type	Level	Pattern	Image	Note
TS21: adrenal gland	chromaffin cell of adrenal gland	Present	Regionally restricted		Expression co-localized with Phox2a in chromaffin cells.

Specimen E13.5 hypo/hypo not shown: embryonic day 13.5; Nr3c1^tm1Gsc/Nr3c1^tm1Gsc (more

)
Note: Data presented in Figs. 2 and 3.

Structure	Level	Pattern	Image	Note
TS21: adrenal gland	Present

Specimen E15.5 wt not shown: embryonic day 15.5 (more

)
Note: Data presented in Fig. 3.

Structure	Level	Pattern	Image	Note
TS23: adrenal gland	Present

Specimen E15.5 hypo/hypo not shown: embryonic day 15.5; Nr3c1^tm1Gsc/Nr3c1^tm1Gsc (more

)
Note: Data presented in Fig. 3.

Structure	Level	Pattern	Image	Note
TS23: adrenal gland	Present

4A ©

Specimen 4A: embryonic day 18.5 (more

)
Note: Additional data presented in Fig. 2 and Table 2.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: adrenal gland	chromaffin cell of adrenal gland	Strong		4A	Expression in all chromaffin cells, co-localized with Phox2a.

4B ©

Specimen 4B: embryonic day 18.5; Nr3c1^tm1Gsc/Nr3c1^tm1Gsc (more

)
Note: Additional data presented in Fig. 2 and Table 2.

Structure	Cell Type	Level	Pattern	Image	Note
TS26: adrenal gland	chromaffin cell of adrenal gland	Strong		4B	Expression in all chromaffin cells.

4C ©

Specimen 4C: embryonic day 18.5; Nr3c1^tm2.1Gsc/Nr3c1^tm2.1Gsc (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS26: adrenal gland	chromaffin cell of adrenal gland	Strong		4C	Expression in all chromaffin cells.

5_TH WT ©

Specimen 5 TH wt: embryonic day 18.5; Nr3c1^tm1Gsc/Nr3c1^tm1Gsc (more

)

Structure	Level	Pattern	Image	Note
TS26: adrenal gland	Present		5_TH WT

Specimen 5 TH null/null: embryonic day 18.5; Nr3c1^tm2.1Gsc/Nr3c1^tm2.1Gsc (more

)

Structure	Level	Pattern	Image	Note
TS26: adrenal gland	Present		5_TH null/null	p

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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