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Gene Expression Data
Assay Details
Assay
Reference: J:278827 Murcia-Belmonte V, et al., A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves. Curr Biol. 2019 Apr 1;29(7):1149-1160.e4
Assay type: RNA in situ
MGI Accession ID: MGI:7709441
Gene symbol: Unc5c
Gene name: unc-5 netrin receptor C
Probe: Unc5c cDNA
Probe preparation: Antisense labelled with Alexa Fluor 647 RNA
Visualized with: Fluorescence
Results
Specimen 3G ventral: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Strong Regionally restricted 3G left upper Highly expressed in ventral areas, excluded from the most peripheral region.
Specimen 3G dorsal: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Strong Regionally restricted 3G right upper Highly expressed in ventral areas and weakly in the dorsal retina.
Specimen 3G nasal: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 3G left lower Expressed at higher levels in the nasal than in the temporal quadrant.
Specimen 3G temporal: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: retina Present Regionally restricted 3G right lower Expressed at higher levels in the nasal than in the temporal quadrant.
Specimen 5A/A': embryonic day 16.5 (more )
Note: Double labeled: red - Unc5c; green - Zic2 (assay MGI:7709448).
Structure Level Pattern Image Note
TS24: retina Strong Regionally restricted 5A , 5A' Highly expressed in ventral areas, excluded from the most peripheral region. Unc5c and Zic2 were expressed in mutually exclusive patterns.
Specimen 5B: embryonic day 16.5; Zic2tm1Jaru/Zic2tm1Jaru (more )
Note: Double labeled: red - Unc5c; green - Zic2 (assay MGI:7709448).
Structure Level Pattern Image Note
TS24: retina Present 5B Expression expanded into the peripheral ventro-temporal territory.
Specimen S2A: embryonic day 16.5 (more )
Note: Double labeled: red - Unc5c; green - Pou4f1 (assay MGI:7709450).
Structure Level Pattern Image Note
TS24: retina ganglion cell layer Present S2A
Specimen S2B: embryonic day 15.5 (more )
Note: Double labeled: red - Unc5c; green - Dcc (assay MGI:7709452).
Structure Level Pattern Image Note
TS23: retina Strong Regionally restricted S2B merge , S2B Unc5c Highly expressed in ventral areas.
TS23: retina ganglion cell layer Strong Regionally restricted S2B merge , S2B Unc5c Highly expressed in ventral areas.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory