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Gene Expression Data
Assay Details
Assay
Reference: J:51420 Sharma K, et al., LIM homeodomain factors Lhx3 and Lhx4 assign subtype identities for motor neurons. Cell. 1998 Dec 11;95(6):817-28
Assay type: RNA in situ
MGI Accession ID: MGI:7709298
Gene symbol: Chat
Gene name: choline O-acetyltransferase
Probe: ChAT probe
Probe preparation: labelled with digoxigenin
Results
Specimen 5c: embryonic day 13.5 (more )
Note: Double labeled: blue - Chat; brown - Isl1 (assay MGI:7709294).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord cervical region motor neuron Present 5c Co-expression with Isl1 in motor neurons in wild type embryos.
Specimen 5d: embryonic day 13.5; Lhx3tm1Lmgd/Lhx3tm1Lmgd, Lhx4tm1Ssp/Lhx4tm1Ssp (more )
Note: Double labeled: blue - Chat; brown - Isl1 (assay MGI:7709294).
Structure Cell Type Level Pattern Image Note
TS21: spinal cord cervical region motor neuron Present Regionally restricted 5d Co-expression with intermedio-lateral Isl1-expressing motor neurons.
TS21: spinal cord cervical region interneuron Absent 5d No expression in dorsal-medial Isl1-expressing interneurons..
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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