About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:76800 North TE, et al., Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity. 2002 May;16(5):661-72
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7707694
Gene symbol: Runx1
Gene name: runt related transcription factor 1
Reporter: lacZ
Direct Detection
Results
Specimen 2A: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Ptprc (assay MGI:7707695).
Structure Cell Type Level Pattern Image Note
TS19: aorta-gonad-mesonephros hematopoietic stem cell Present 2A 10x , 2A 60x Expression in Ptprc-expressing hematopoietic stem cells in paraaortic mesenchyme.
TS19: aorta-gonad-mesonephros mesenchymal cell Present 2A 60x , 2A 10x
TS19: aorta-gonad-mesonephros endothelial cell Present Regionally restricted 2A 10x , 2A 60x Expression in endothelial cells that do not express Ptprc.
Specimen 3A left: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A left
Specimen 3A left-middle: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Pecam1 (assay MGI:7707697).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A left-middle
Specimen 3A middle-right: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Kdr (assay MGI:7707698).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A middle-right
Specimen 3A right: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Cdh5 (assay MGI:7707699).
Structure Level Pattern Image Note
TS19: aorta-gonad-mesonephros Present 3A right
Specimen 4B: embryonic day 11.5; Runx1tm2Spe/Runx1+ (more )
Note: Double labeled: blue - Runx1 reporter; brown - Kit (assay MGI:7707700).
Structure Cell Type Level Pattern Image Note
TS19: aorta-gonad-mesonephros endothelial cell Present 4B Co-expression with Kit in endothelial cells
TS19: aorta-gonad-mesonephros mesenchymal cell Present Regionally restricted 4B Co-expression with Kit n mesenchymal cells directly under the endothelium.
TS19: aorta-gonad-mesonephros hematopoietic stem cell Present Regionally restricted 4B Co-expression with Kit in intraaortic hemaptopoietic clusters.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory