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Gene Expression Data
Assay Details
Assay
Reference: J:111429 Feng JQ, et al., Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31
Assay type: RNA in situ
MGI Accession ID: MGI:7705075
Gene symbol: Bglap
Gene name: bone gamma carboxyglutamate protein
Probe: OC probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 5A Wt: embryonic day 16.5 (more )
Structure Cell Type Level Pattern Image Note
TS24: femur osteoblast Present 5A Wt
Specimen 5A Cbfa1-/-: embryonic day 16.5; Runx2tm1Kish/Runx2tm1Kish (more )
Structure Level Pattern Image Note
TS24: femur Absent 5A Cbfa1-/- No expression in developing bones.
Specimen 5B Wt: embryonic day 18.0 (more )
Structure Cell Type Level Pattern Image Note
TS26: tooth osteoblast Present 5B Wt
Specimen 5B Cbfa1-/-: embryonic day 18.0; Runx2tm1Kish/Runx2tm1Kish (more )
Structure Level Pattern Image Note
TS26: tooth Absent 5B Cbfa1-/- No expression in the arrested tooth tissues.
Specimen 7C left: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: femur Absent 7C left No expression in chondrocytes or osteocytes.
Specimen 7C middle: postnatal week 2 (more )
Structure Cell Type Level Pattern Image Note
TS28: bone osteoblast Present 7C middle
Specimen 7C right: postnatal week 2 (more )
Structure Level Pattern Image Note
TS28: cartilage Absent 7C right No expression in chondrocytes or osteocytes.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory