Runx2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:111429 Feng JQ, et al., Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31
Assay type:	RNA in situ
MGI Accession ID:	MGI:7705073
Gene symbol:	Runx2
Gene name:	runt related transcription factor 2

Probe:	Cbfa1 probe
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

Specimen 1A Cbfa1: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: cartilage condensation	Strong		1A Cbfa1	Highly expressed in developing cartilage tissues.

Specimen 1B Cbfa1: embryonic day 14.5 (more

)

Structure	Level	Pattern	Image	Note
TS22: cartilage condensation	Strong		1B Cbfa1	High level of expression in cartilaginous tissues.

Specimen 1C Cbfa1: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: embryo	Present	Regionally restricted	1C Cbfa1

Specimen 1D1: embryonic day 16.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS24: chondrocranium	hypertrophic chondrocyte	Present		1D1

Specimen 1D2: embryonic day 16.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS24: vertebra	osteoblast	Present		1D2

Specimen 1D3 upper: embryonic day 16.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS24: rib	hypertrophic chondrocyte	Present		1D3 upper

Specimen 1D3 lower left: embryonic day 16.5 (more

)

Structure	Level	Pattern	Image	Note
TS24: rib	Present	Regionally restricted	1D3 lower left	Expression in areas of cartilage not undergoing mineratization.

Specimen 1D3 lower right: embryonic day 16.5 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS24: rib	hypertrophic chondrocyte	Present		1D3 lower right

Specimen 7A left: postnatal week 2 (more

)

Structure	Level	Pattern	Image	Note
TS28: femur	Absent		7A left	Expression virtually undetectable.

Specimen 7A middle: postnatal week 2 (more

)

Structure	Level	Pattern	Image	Note
TS28: bone	Absent		7A middle	Expression virtually undetectable.

Specimen 7A right: postnatal week 2 (more

)

Structure	Level	Pattern	Image	Note
TS28: cartilage	Absent		7A right	Expression virtually undetectable.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/25/2025 MGI 6.24