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Gene Expression Data
Assay Details
Assay
Reference: J:45357 Jemtland R, et al., Heterogeneity among cells that express osteoclast-associated genes in developing bone. Endocrinology. 1998 Jan;139(1):340-9
Assay type: RNA in situ
MGI Accession ID: MGI:7703509
Gene symbol: Mmp9
Gene name: matrix metallopeptidase 9
Probe: 92-kDa type IV collagenase probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1d: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: tibia Present Regionally restricted 1d Expressed earlier than c-fms or TRAP.

Specimen 1e/f: embryonic day 15.0 (more )
Structure Level Pattern Image Note
TS23: perichondrium Strong Regionally restricted 1e , 1f Highly expressed in discrete cells in or immediately outside the perichondrium/periosteum, in proximity of bone collar.
TS23: periosteum Strong Regionally restricted 1e , 1f Highly expressed in discrete cells in or immediately outside the perichondrium/periosteum, in proximity of bone collar.

Specimen 2i/j,k/l: embryonic day 16.0 (more )
Structure Level Pattern Image Note
TS24: perichondrium Present Regionally restricted 2i , 2j , 2k , 2l Expression in cells along inner and outer layears of bone collar and flanking perichondium/periosteum.
TS24: periosteum Present Regionally restricted 2i , 2j , 2k , 2l Expression in cells along inner and outer layears of bone collar and flanking perichondium/periosteum.
TS24: tibia Present Regionally restricted 2i , 2j , 2k , 2l Expression in cells along inner and outer layears of bone collar and flanking perichondium/periosteum.

Specimen 3d: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: tibia Present Regionally restricted 3d

Specimen 4e/f: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: tibia Present Regionally restricted 4e , 4f Authors report distinct localization of expression type IV collagenase and TRAP.

Specimen 5b/c: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: tibia Present Regionally restricted 5c , 5b Expression highest in cells at chondro-osseus border.

Specimen 6e/f: postnatal day 5 (more )
Structure Level Pattern Image Note
TS28: tibia Present Regionally restricted 6e , 6f Expression in cells at chondro-osseus margin.

Specimen 7Ac/f: postnatal day 15 (more )
Structure Level Pattern Image Note
TS28: tibia Present Regionally restricted 7Af , 7Ac Expression more intense at junction between cartilage and bone than in the diaphysis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/30/2025
MGI 6.24
The Jackson Laboratory