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Gene Expression Data
Assay Details
Assay
Reference: J:87223 Buttitta L, et al., Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction. Development. 2003 Dec;130(25):6233-43
Assay type: RNA in situ
MGI Accession ID: MGI:7703163
Gene symbol: Sox9
Gene name: SRY (sex determining region Y)-box 9
Probe: Sox9 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A'': embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: sclerotome Present Regionally restricted 2A'' Expression is in both ventral and dorsal domains of the sclerotome in anterior somites.
Specimen 2B'': embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS15: sclerotome Present Non-Uniform 2B'' In this mutant expression is reduced in both ventral and dorsal domains of anterior somites.
Specimen 2C'': embryonic day 9.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS15: sclerotome Present Non-Uniform 2C'' In this mutant expression is reduced in the anterior somites, with the dorsal region most affected.
Specimen 2D'': embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3+ (more )
Structure Level Pattern Image Note
TS15: sclerotome Present Non-Uniform 2D'' In this mutant expression is reduced in both ventral and dorsal domains of anterior somites.
Specimen 2E'': embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS15: sclerotome Absent 2E''
Specimen S1B WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: sclerotome Present S1B WT
Specimen S1B Gli2-/-: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj (more )
Structure Level Pattern Image Note
TS15: sclerotome Present S1B Gli2-/-
Specimen S1B Gli3-/-: embryonic day 9.5; Gli3Xt-J/Gli3Xt-J (more )
Structure Level Pattern Image Note
TS15: sclerotome Present S1B Gli3-/-
Specimen S1B Gli2-/-Gli3+/-: embryonic day 9.5; Gli2tm1Alj/Gli2tm1Alj, Gli3Xt-J/Gli3+ (more )
Structure Level Pattern Image Note
TS15: sclerotome Present S1B Gli2-/-Gli3+/-
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory