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Gene Expression Data
Assay Details
Assay
Reference: J:44495 Karg H, et al., Spatiotemporal expression of the homeobox gene S8 during mouse tooth development. Arch Oral Biol. 1997 Sep;42(9):625-31
Assay type: RNA in situ
MGI Accession ID: MGI:7657390
Gene symbol: Prrx2
Gene name: paired related homeobox 2
Probe: S8 probe
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Probe length was reduced to an average length of 200 bp by limited alkaline hydrolysis.
Results
Specimen 1A: embryonic day 14.0 (more )
Note: Early cap stage maxillary first molar.
Structure Level Pattern Image Note
TS22: upper jaw molar mesenchyme Strong Non-Uniform 1A Expression is stronger in the central area of the condensed dental mesenchyme.
TS22: 1st molar Present 1A
TS22: dental sac Present 1A
Specimen 1C: embryonic day 15.5 (more )
Note: Early bell stage of tooth development.
Structure Level Pattern Image Note
TS23: dental sac Strong 1C
TS23: lower jaw molar dental papilla Strong 1C
TS23: upper jaw molar dental papilla Strong 1C
Specimen 1E: embryonic day 16.5 (more )
Note: Mid bell stage of tooth development.
Structure Level Pattern Image Note
TS24: 2nd molar Strong 1E
TS24: molar mesenchyme Present 1E
TS24: 1st molar Weak 1E
Specimen 2A: embryonic day 14.0 (more )
Note: Advanced cap stage of tooth development.
Structure Level Pattern Image Note
TS22: upper jaw incisor dental papilla Present 2A
TS22: incisor enamel organ Absent 2A
TS22: molar enamel organ Absent 2A
Specimen 2C: embryonic day 15.5 (more )
Note: Early bell stage of tooth development.
Structure Cell Type Level Pattern Image Note
TS23: incisor mesenchyme Strong 2C
TS23: lower jaw incisor dental papilla preodontoblast Strong 2C Including the preodontoblast layer.
TS23: dental sac Moderate 2C
TS23: lower jaw Weak Regionally restricted 2C Expression is in alveolar bone surrounding the incisor tooth germ.
TS23: Meckel's cartilage Absent 2C
TS23: lower jaw incisor enamel organ Absent 2C
Specimen 2E: embryonic day 16.5 (more )
Note: Advanced bell stage of tooth development.
Structure Cell Type Level Pattern Image Note
TS24: lower jaw incisor dental papilla preodontoblast Strong Regionally restricted 2E Expression is in preodontoblasts in cervical loop areas.
TS24: lower jaw skeleton Weak Regionally restricted 2E Expression is in the alveolar bone.
Specimen not shown: embryonic day 13.0 (more )
Note: Bud stage molar.
Structure Level Pattern Image Note
TS21: 1st molar Weak Regionally restricted Expression is throughout the condensing dental mesenchyme surrounding the invaginating dental epithelium.
TS21: lower jaw 1st molar Weak Regionally restricted Expression is throughout the condensing dental mesenchyme surrounding the invaginating dental epithelium.
TS21: lower jaw molar mesenchyme Weak Regionally restricted Expression is throughout the condensing dental mesenchyme surrounding the invaginating dental epithelium.
TS21: upper jaw molar Weak Regionally restricted Expression is throughout the condensing dental mesenchyme surrounding the invaginating dental epithelium.
TS21: upper jaw molar mesenchyme Weak Regionally restricted Expression is throughout the condensing dental mesenchyme surrounding the invaginating dental epithelium.
TS21: lower jaw molar epithelium Absent
TS21: upper jaw molar epithelium Absent
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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