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Gene Expression Data
Assay Details
Assay
Reference: J:299191 Kitazawa M, et al., Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7645160
Gene symbol: Actn2
Gene name: actinin alpha 2
Antibody: anti alpha-actinin (EA-53)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S8A Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Actn2; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: abdomen musculature Present Regionally restricted S8A Mat-Rtl1 delta Merge , S8A Mat-Rtl1 delta alpha-Actinin Expression was detected at the sarcomeric Z-disc. Expression pattern was similar to that of Rtl1, but was not merged.
Specimen S8B Mat-Rtl1 delta: postnatal newborn; Rtl1tm1Fuis/Rtl1tm1Fuis (more )
Note: Deletion upon maternal transmission. Double labeled: green - Actn2; red - Rtl1 (assay MGI:7643794).
Structure Level Pattern Image Note
TS27: abdomen musculature Present Regionally restricted S8B Mat-Rtl1 delta Merge , S8B Mat-Rtl1 delta alpha-Actinin Expression was detected at the sarcomeric Z-disc. Expression pattern was similar to that of Rtl1, but was not merged.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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