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Gene Expression Data
Assay Details
Assay
Reference: J:312371 Da Silva F, et al., Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex. EMBO J. 2021 Oct 1;40(19):e108041
Assay type: Western blot
MGI Accession ID: MGI:7643175
Gene symbol: Lrp6
Gene name: low density lipoprotein receptor-related protein 6
Antibody: Phospho-LRP6 (Ser1490) Antibody #2568
Detection system: Secondary antibody coupled to horseradish peroxidase
Assay notes: The antibody used recognizes the phosphorylated form of the protein.
Results
Image: 1N pLRP6 ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified (a) Genetic BackgroundMutant Allele(s)Sex
Co E13.5 TS21: forebrain Present involves: C57BL/6N Ccnytm1.1Smoc/Ccny+, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1+Not Specified
DKO E13.5 TS21: forebrain Present (b) involves: C57BL/6N Ccnytm1.1Smoc/Ccnytm1.1Smoc, Ccnyl1tm1a(EUCOMM)Wtsi/Ccnyl1tm1a(EUCOMM)WtsiNot Specified
Notes:
(a) Numbers above blot indicate fold change vs. controls of phospho-LRP6 (S1490) protein levels normalized to total LRP6.
(b) Reduced (-45%) expression compared with the controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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