Gene Expression Data
Assay Details
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Assay
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Reference:
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J:43652
Deiner MS, et al., Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia. Neuron. 1997 Sep;19(3):575-89
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7643163
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Gene symbol:
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L1cam
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Gene name:
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L1 cell adhesion molecule
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Antibody:
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anti-L1
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Detection system:
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Secondary antibody coupled to Cy3
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Results
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Specimen
1l:
embryonic day 14.5
(more  )
Specimen
1l:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: optic disc |
Present |
Regionally restricted |
1l
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Expression in retinal axons at optic disc.
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Specimen
5f:
embryonic day 14.5
(more )
Specimen
5f:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: retina ganglion cell layer |
retinal ganglion cell |
Present |
Regionally restricted |
5f
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Expression in retinal ganglion cell (RGC) axons in optic fiber layer.
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| TS22: optic disc |
retinal ganglion cell |
Present |
Regionally restricted |
5f
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Expression in retinal ganglion cell (RGC) axons exiting though optic disc.
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Specimen
5g:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: optic disc |
retinal ganglion cell |
Present |
Regionally restricted |
5g
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Expression in retinal ganglion cell (RGC) axons comparable to control embryos.
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| TS22: retina |
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Present |
Regionally restricted |
5g
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Expression in retinal ganglion cell (RGC) axon bundles not restricted to optic fiber layer and instead penetrated through thickness of retina.
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Specimen
5h:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: intraretinal space |
retinal ganglion cell |
Present |
Regionally restricted |
5h
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Expression in ectopic bundle of retinal ganglion cell (RGC) axons penetrating though retina into subretinal space.
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Specimen
5i:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd
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Mutant Allele(s):
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Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
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Age:
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embryonic day 14.5
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Age Note:
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Age normalized so that noon of plug day = E0.5.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS22: pigmented retinal epithelium |
retinal ganglion cell |
Present |
Regionally restricted |
5i
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Expression in ectopic retinal ganglion cell (RGC) axon bundle extending from subretinal space into retinal pigment epithelium (RPE), inserting bewteen pigmented RPE cells.
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Analysis Tools
