About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:180909 Hoste E, et al., Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol. 2011 Nov;131(11):2233-41
Assay type: Western blot
MGI Accession ID: MGI:7641806
Gene symbol: Flg
Gene name: filaggrin
Antibody: anti-FLG
Detection system: Secondary antibody coupled to horseradish peroxidase
Results Image: 1a
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Genetic BackgroundMutant Allele(s)Sex
P5.5 +/+ P5.5 TS28: skin Present Not Specified Not Specified
P5.5 -/- P5.5 TS28: skin Strong (a) Not Specified Casp14tm1Wdec/Casp14tm1WdecNot Specified
Adult +/+ P adult TS28: skin Present Not Specified Not Specified
Adult -/- P adult TS28: skin Present (a) Not Specified Casp14tm1Wdec/Casp14tm1WdecNot Specified
Notes:
(a) In this mutant there is an accumulation of Flg-derived peptides compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory