Gene Expression Data
Assay Details
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Assay
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Reference:
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J:37450
Studer M, et al., Altered segmental identity and abnormal migration of motor neurons in mice lacking Hoxb-1. Nature. 1996 Dec 19-26;384(6610):630-4
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7640209
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Gene symbol:
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Ret
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Gene name:
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ret proto-oncogene
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Probe:
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Ret probe
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
E12.5 +/+ not shown:
embryonic day 12.5
(more )
Specimen
E12.5 +/+ not shown:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: facial nerve |
Present |
Regionally restricted |
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Expression in facial branchiomotor neurons along midline.
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Specimen
E12.5 -/- not shown:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Hoxb1tm2Brd/Hoxb1tm2Brd
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: facial nerve |
Absent |
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Expression not detected in facial branchiomotor neurons along midline.
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Specimen
4e:
embryonic day 15.5
(more )
Specimen
4e:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
4f:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6
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Mutant Allele(s):
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Hoxb1tm2Brd/Hoxb1tm2Brd
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: facial nucleus |
Trace |
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4f
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Expression greatly diminished and then lost in mutant embryos. Weak expression in facial nucleus.
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