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Gene Expression Data
Assay Details
Assay
Reference: J:306261 Kim CH, et al., NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development. Nucleic Acids Res. 2021 Jun 4;49(10):5760-5778
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7639935
Gene symbol: Cd8a
Gene name: CD8 subunit alpha
Antibody: anti-CD8alpha
Results
Specimen 2B WT: postnatal week 6 (more )
Note: Double labeled: red - Cd8a; green - Cd4 (assay MGI:7639934).
Structure Level Pattern Image Note
TS28: thymus Present 2B WT CD8 , 2B WT merged , 2B WT (enlarged) , 2B WT
Specimen 2B KO: postnatal week 6; Nsrp1tm1.1Cdj/Nsrp1tm1.1Cdj, Tg(Cd4-cre)1Cwi/0 (more )
Note: Conditional mutant. Double labeled: red - Cd8a; green - Cd4 (assay MGI:7639934).
Structure Level Pattern Image Note
TS28: thymus Present 2B KO , 2B KO merged , 2B KO CD8 , 2B KO (enlarged)
Specimen 2C Spleen WT: postnatal week 6 (more )
Note: Double labeled: red - Cd8a; green - Cd4 (assay MGI:7639934).
Structure Level Pattern Image Note
TS28: spleen Present 2C Spleen WT
Specimen 2C Spleen KO: postnatal week 6; Nsrp1tm1.1Cdj/Nsrp1tm1.1Cdj, Tg(Cd4-cre)1Cwi/0 (more )
Note: Conditional mutant. Double labeled: red - Cd8a; green - Cd4 (assay MGI:7639934).
Structure Level Pattern Image Note
TS28: spleen Weak 2C Spleen KO
Specimen 2C Lymph node WT: postnatal week 6 (more )
Note: Double labeled: red - Cd8a; green - Cd4 (assay MGI:7639934).
Structure Level Pattern Image Note
TS28: lymph node Present 2C Lymph node WT
Specimen 2C Lymph node KO: postnatal week 6; Nsrp1tm1.1Cdj/Nsrp1tm1.1Cdj, Tg(Cd4-cre)1Cwi/0 (more )
Note: Conditional mutant. Double labeled: red - Cd8a; green - Cd4 (assay MGI:7639934).
Structure Level Pattern Image Note
TS28: lymph node Weak 2C Lymph node KO
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory