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Gene Expression Data
Assay Details
Assay
Reference: J:346442 Migale R, et al., FOXL2 interaction with different binding partners regulates the dynamics of ovarian development. Sci Adv. 2024 Mar 22;10(12):eadl0788
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7628319
Gene symbol: Usp7
Gene name: ubiquitin specific peptidase 7
Antibody: anti-USP7 (A300-033A)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen S15B Control: postnatal day 0; Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS27: ovary follicle cell Present Regionally restricted S15B Control FOXL2/USP7 , S15B Control USP7 Expression co-localized with Foxl2 in somatic cells.
TS27: oocyte Strong S15B Control FOXL2/USP7 , S15B Control USP7
Specimen S15B Sf1:Cretg/+;Usp7fl/fl: postnatal day 0; Tg(Nr5a1-cre)2Klp/0, Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Conditional mutant. Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS27: follicle cell of primordial follicle Absent S15B Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 , S15B Sf1:Cretg/+;Usp7fl/fl USP7 Expression not detected in somatic cells arrested in primordial follicle.
TS27: oocyte Strong S15B Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 , S15B Sf1:Cretg/+;Usp7fl/fl USP7
Specimen S15C Control: postnatal day 7; Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS28: ovary follicle cell Present S15C Control FOXL2/USP7 , S15C Control USP7 Expression co-localized with Foxl2 in somatic cells.
TS28: oocyte Strong S15C Control USP7 , S15C Control FOXL2/USP7
Specimen S15C Sf1:Cretg/+;Usp7fl/fl: postnatal day 7; Tg(Nr5a1-cre)2Klp/0, Usp7tm2Wgu/Usp7tm2Wgu (more )
Note: Conditional mutant. Double labeled: red - Usp7; green - Foxl2 (assay MGI:7628312).
Structure Level Pattern Image Note
TS28: follicle cell of primordial follicle Absent S15C Sf1:Cretg/+;Usp7fl/fl USP7 , S15C Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 Expression not detected in somatic cells arrested in primordial follicle.
TS28: oocyte Strong S15C Sf1:Cretg/+;Usp7fl/fl USP7 , S15C Sf1:Cretg/+;Usp7fl/fl FOXL2/USP7 Expression not detected in somatic cells arrested in primordial follicle.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory