About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:306034 Troy TC, et al., Re-assessing K15 as an epidermal stem cell marker. Stem Cell Rev Rep. 2011 Nov;7(4):927-34
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7628029
Gene symbol: Krt15
Gene name: keratin 15
Antibody: anti-K15 (UC55)
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 1a: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: oral epithelium Present Regionally restricted 1a Expression mostly restricted to undifferentiated basal cells of keratinizing oral epithelium of roof of mouth.

Specimen 1b: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: oral epithelium Present Regionally restricted 1b Expression in many layers of non-keratinizing oral epithelium.

Specimen 1c: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: tongue keratinized epithelium Present Regionally restricted 1c Expression localized to undifferentiated basal cells of keratinized stratified squamous epithelium on dorsal surface of tongue.

Specimen 1d: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: tongue epithelium Present Regionally restricted 1d Expression in continuous non-keratinized epithelium on ventral surface of tongue.

Specimen 1e: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: stomach proventricular region epithelium Present Regionally restricted 1e Expression in stratified epithelium of forestomach.
TS27: stomach glandular region epithelium Absent 1e No expression in simple columnar epithelium of glandular compartment of stomach.

Specimen 1f: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: vibrissa follicle Present Regionally restricted 1f Expression in several layers of whisker follicle.

Specimen 1h: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: proximal nail fold Present Regionally restricted 1h Expression only in basal compartment of proximal nail fold.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: surface ectoderm Absent No expression in ectodermal layer of embryo.

Specimen 2a: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: epidermis basal layer Present 2a Expression in basal cell layer of ectoderm and overlying periderm.
TS20: periderm Present 2a Expression in basal cell layer of ectoderm and overlying periderm.

Specimen 2b: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: epidermis basal layer Present 2b Expression in basal cell layer of ectoderm and overlying periderm.
TS21: periderm Present 2b Expression in basal cell layer of ectoderm and overlying periderm.
TS21: epidermis Present Regionally restricted 2b No expression in intermediate cells between basal layer and periderm.

Specimen 2c: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: epidermis basal layer Present Regionally restricted 2c Expression in basal cell layer of ectoderm and overlying periderm.
TS22: periderm Present Regionally restricted 2c Expression in basal cell layer of ectoderm and overlying periderm.
TS22: epidermis Present Regionally restricted 2c No expression in an intermediate layer of cells between basal layer and periderm.
TS22: hair epidermal placode Absent 2c No expression where initial peg formation is evident.

Specimen 2d: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: epidermis basal layer Present 2d Expression in basal cell layer of ectoderm.
TS23: periderm Very strong 2d Very strong expression in overlying periderm.
TS23: hair germ Present Regionally restricted 2d Expression in cells emerging into peg of developing hair follicle.

Specimen 2e: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: epidermis basal layer Present 2e Expression in basal cell layer of ectoderm.
TS24: periderm Very strong 2e Very strong expression in overlying periderm.
TS24: hair peg Present 2e Expression in cells emerging into peg of developing hair follicle.

Specimen 2f: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis basal layer Present 2f Expression in basal cell layer of ectoderm.
TS25: hair peg Present Regionally restricted 2f As hair peg elongates, leading edge of expression restricted to outer root sheath.

Specimen 2g: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: epidermis basal layer Present 2g Expression in basal cell layer of ectoderm.
TS26: hair peg Present Regionally restricted 2g As hair peg elongates, leading edge of expression restricted to outer root sheath.

Specimen 2h: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: epidermis basal layer Present 2h Expression in basal cell layer of ectoderm.
TS27: hair outer root sheath Present Regionally restricted 2h As hair peg elongates, leading edge of expression restricted to outer root sheath.
TS27: hair peg Present Regionally restricted 2h As hair peg elongates, leading edge of expression restricted to outer root sheath.

Specimen 2i: postnatal adult (more )
Structure Level Pattern Image Note
TS28: hair outer root sheath Present 2i Expression restricted to outer root sheath
TS28: hair bulb Present Regionally restricted 2i Expression restricted to base of hair bulb.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory