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Gene Expression Data
Assay Details
Assay
Reference: J:264015 Roy AR, et al., The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells. J Biol Chem. 2018 Jun 1;293(22):8449-8461
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7624267
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: MEC 13.3
Results
Specimen S1F Ctcf fl/fl (upper): embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS17: blood vessel Present S1F Ctcf fl/fl (upper)
Specimen S1F Ctcf fl/fl; Tie2-Cre (upper): embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: blood vessel Present S1F Tie2-Cre (upper) Authors report an overall normal vasculature pattern.
Specimen S1F Ctcf fl/fl (lower): embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: blood vessel Present S1F Ctcf fl/fl (lower)
Specimen S1F Ctcf fl/fl; Tie2-Cre (lower): embryonic day 10.5; Ctcftm2Gal/Ctcf+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: blood vessel Present S1F Tie2-Cre (lower) Authors report an overall normal vasculature pattern.
Specimen 1C E9.5 Ctcf fl/fl Right: embryonic day 9.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS15: head blood vessel Present 1C E9.5 fl/fl Right
Specimen 1C E9.5 Ctcf fl/fl Left: embryonic day 9.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS15: head blood vessel Present 1C E9.5 fl/fl Left
Specimen 1C 9.5 Ctcf fl/fl; Tie2-Cre Right: embryonic day 9.5; Ctcftm2Gal/Ctcf+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: head blood vessel Present 1C E9.5 Tie2-Cre Right Number of major branches of cerebral vasculatuer comparable between control and mutant embryos.
Specimen 1C 9.5 Ctcf fl/fl; Tie2-Cre Left: embryonic day 9.5; Ctcftm2Gal/Ctcf+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: head blood vessel Present 1C E9.5 Tie2-Cre Left Number of major branches of cerebral vasculatuer comparable between control and mutant embryos.
Specimen 1C E10.5 Ctcf fl/fl Right: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS17: head blood vessel Present 1C E10.5 fl/fl Right
Specimen 1C E10.5 Ctcf fl/fl Left: embryonic day 10.5; Ctcftm2Gal/Ctcftm2Gal (more )
Structure Level Pattern Image Note
TS17: head blood vessel Present 1C E10.5 fl/fl Left
Specimen 1C E10.5 Ctcf fl/fl; Tie2-Cre Right: embryonic day 10.5; Ctcftm2Gal/Ctcf+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: head blood vessel Present 1C E10.5 Tie2-Cre Right Number of major branches of cerebral vasculatuer comparable between control and mutant embryos.
Specimen 1C E10.5 Ctcf fl/fl; Tie2-Cre Left: embryonic day 10.5; Ctcftm2Gal/Ctcf+, Tg(Tek-cre)#Rwng/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: head blood vessel Present 1C E10.5 Tie2-Cre Left Number of major branches of cerebral vasculatuer comparable between control and mutant embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory