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Gene Expression Data
Assay Details
Assay
Reference: J:74183 Kieffer-Combeau S, et al., Cell-matrix interactions and cell-cell junctions during epithelial histo-morphogenesis in the developing mouse incisor. Int J Dev Biol. 2001 Sep;45(5-6):733-42
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7621253
Gene symbol: Lamc2
Gene name: laminin, gamma 2
Antibody: SE144
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 7P: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: basement membrane Present Regionally restricted 7P Expression is in the basement membrane in contact with the outer enamel epithelium on the labial side of the incisor.
TS26: outer enamel epithelium Present Regionally restricted 7P Expression is in the basement membrane in contact with the outer enamel epithelium on the labial side of the incisor.
TS26: cervical loop Present Regionally restricted 7P Absent in the labial part.
TS26: incisor Present Regionally restricted 7P Absent in the lingual part.

Specimen 7Q: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: basement membrane Present Regionally restricted 7Q Expression is in the basement membrane in contact with the outer enamel epithelium on the labial side of the incisor.
TS26: outer enamel epithelium Present Regionally restricted 7Q Expression is in the basement membrane in contact with the outer enamel epithelium on the labial side of the incisor.
TS26: cervical loop Present Regionally restricted 7Q Absent in the labial part.
TS26: incisor Present Regionally restricted 7Q Absent in the lingual part.

Specimen 7R: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cervical loop Present Regionally restricted 7R Absent in the labial part.
TS26: incisor Present Regionally restricted 7R Absent in the lingual part.

Specimen 8D: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: basement membrane Present Regionally restricted 8D Expression is in the basement membrane in contact with the inner and outer enamel epithelium and was weaker in the lingual side of the cervical loop.
TS22: cervical loop Present Regionally restricted 8D Expression is in the basement membrane in contact with the inner and outer enamel epithelium and was weaker in the lingual side of the cervical loop.
TS22: incisor epithelium Present Regionally restricted 8D Expression is in the basement membrane in contact with the inner and outer enamel epithelium and was weaker in the lingual side of the cervical loop.

Specimen 8E: embryonic day 16.0 (more )
Note: Early bell stage of tooth development.
Structure Level Pattern Image Note
TS24: basement membrane Present Regionally restricted 8E , 8F Except in the most anterior part of the incisor, expression decreased in the basement membrane associated with the inner dental epithelium.
TS24: inner enamel epithelium Present Regionally restricted 8E , 8F Except in the most anterior part of the incisor, expression decreased in the basement membrane associated with the inner dental epithelium.
TS24: cervical loop Weak Regionally restricted 8F , 8E Expression is on the labial side.

Specimen 9C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: basement membrane Strong Regionally restricted 9C Expression is in the basement membrane and is stronger in cells in contact with the enamel knot.
TS22: enamel knot Strong Regionally restricted 9C Expression is in the basement membrane and is stronger in cells in contact with the enamel knot.
TS22: incisor epithelium Strong Regionally restricted 9C Expression is in the basement membrane and is stronger in cells in contact with the enamel knot.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory