Gene Expression Data
Assay Details
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Assay
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Reference:
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J:83752
Cox PR, et al., Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory. Mol Cell Neurosci. 2003 May;23(1):1-12
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:7618459
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Gene symbol:
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Tmod1
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Gene name:
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tropomodulin 1
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Antibody:
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anti-Tmod1
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Detection system:
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Secondary antibody coupled to horseradish peroxidase
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Assay notes:
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This assay was displayed as using A12 line (Tmod2<tm1Hzo>). It is possible that the B3 line (Tmod2<tm2Hzo>) could be used as well.
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Results
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Specimen
6B +/+:
postnatal
(more  )
Specimen
6B +/+:
(close  )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
6B -/-:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Tmod2tm1Hzo/Tmod2tm1Hzo
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: hippocampus CA1 |
Present |
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6B -/-
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Increased expression compared with the wild-type.
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| TS28: brain |
Present |
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6B -/-
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Increased expression compared with the wild-type.
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Specimen
6C +/+:
postnatal
(more )
Specimen
6C +/+:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
6C -/-:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Tmod2tm1Hzo/Tmod2tm1Hzo
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
not shown +/+:
postnatal
(more )
Specimen
not shown +/+:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
not shown -/-:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd * C57BL/6J
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Mutant Allele(s):
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Tmod2tm1Hzo/Tmod2tm1Hzo
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Age:
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postnatal
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cerebral cortex |
Present |
Regionally restricted |
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Increased expression in the lower layers compared with the wild-type.
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Analysis Tools