About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:83752 Cox PR, et al., Mice lacking Tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory. Mol Cell Neurosci. 2003 May;23(1):1-12
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7618378
Gene symbol: Tmod2
Gene name: tropomodulin 2
Reporter: lacZ
Direct Detection
Assay notes: This assay was displayed as using A12 line (Tmod2<tm1Hzo>). It is possible that the B3 line (Tmod2<tm2Hzo>) could be used as well.
Results
Specimen 2A: postnatal adult; Tmod2tm1Hzo/Tmod2+ (more )
Note: vibratome section
Structure Level Pattern Image Note
TS28: brainstem nucleus Present 2A
TS28: caudate nucleus Present 2A
TS28: cerebellum Present 2A
TS28: cerebral cortex Present 2A
TS28: dentate gyrus Present 2A
TS28: hippocampus CA1 Present 2A
TS28: hippocampus CA3 Present 2A
TS28: main olfactory bulb Present 2A
TS28: putamen Present 2A
TS28: tectum Present 2A
Specimen 2B -/-: embryonic day 11.5; Tmod2tm1Hzo/Tmod2tm1Hzo (more )
Structure Level Pattern Image Note
TS19: brain Present 2B -/-
TS19: future spinal cord Present 2B -/-
Specimen 2B +/-: embryonic day 11.5; Tmod2tm1Hzo/Tmod2+ (more )
Structure Level Pattern Image Note
TS19: brain Present 2B +/-
TS19: future spinal cord Present 2B +/-
Specimen 2C -/-: embryonic day 11.5; Tmod2tm1Hzo/Tmod2tm1Hzo (more )
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted 2C -/- Expressed in the ventral aspect.
TS19: notochord Present 2C -/-
Specimen 2C +/-: embryonic day 11.5; Tmod2tm1Hzo/Tmod2+ (more )
Structure Level Pattern Image Note
TS19: neural tube Present Regionally restricted 2C +/- Expressed in the ventral aspect.
TS19: notochord Present 2C +/-
Specimen 2D: embryonic day 11.5; Tmod2tm1Hzo/Tmod2tm1Hzo (more )
Structure Level Pattern Image Note
TS19: neural retina Present Regionally restricted 2D Expressed in the inner neuroblastic layer, which gives rise to the retinal ganglion cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory