About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:74283 Chan R, et al., The Catalytic Activity of the ErbB-2 Receptor Tyrosine Kinase Is Essential for Embryonic Development. Mol Cell Biol. 2002 Feb;22(4):1073-8
Assay type: RNA in situ
MGI Accession ID: MGI:7616838
Gene symbol: Phox2a
Gene name: paired-like homeobox 2a
Probe: Phox2a probe
Probe preparation: Antisense RNA
Assay notes: Fixation was 4% paraformaldehyde. 0.2% glutaraldehyde.
Results
Specimen 4A: embryonic day 10.0-10.5 (more )
Structure Level Pattern Image Note
TS16: peripheral nervous system ganglion Present Regionally restricted 4A Authors report normal sympathetic chain ganglia development.

Specimen 4B: embryonic day 10.5-11.0 (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system ganglion Present Regionally restricted 4B Authors report normal sympathetic chain ganglia development.

Specimen 4C: embryonic day 10.0-10.5; Erbb2tm1Mul/Erbb2+ (more )
Structure Level Pattern Image Note
TS16: peripheral nervous system ganglion Present Regionally restricted 4C Authors report normal sympathetic chain ganglia development.

Specimen 4D: embryonic day 10.5-11.0; Erbb2tm1Mul/Erbb2+ (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system ganglion Present Regionally restricted 4D Authors report normal sympathetic chain ganglia development.

Specimen 4E: embryonic day 10.0-10.5; Erbb2tm1Mul/Erbb2tm1Mul (more )
Structure Level Pattern Image Note
TS16: peripheral nervous system ganglion Weak Regionally restricted 4E Weak expression in rostral-most region of sympathetic chain.

Specimen 4F: embryonic day 10.5-11.0; Erbb2tm1Mul/Erbb2tm1Mul (more )
Structure Level Pattern Image Note
TS17: embryo Absent 4F Expression completely absent in embryo.

Specimen 4G: embryonic day 10.0-10.5; Erbb2tm2Mul/Erbb2tm2Mul (more )
Structure Level Pattern Image Note
TS16: peripheral nervous system ganglion Ambiguous 4G Sympathetic chain appears to be absent.

Specimen 4H: embryonic day 10.5-11.0; Erbb2tm2Mul/Erbb2tm2Mul (more )
Structure Level Pattern Image Note
TS17: peripheral nervous system ganglion Present Regionally restricted 4H Authors report development of a lengthy sympathetic chain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory