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Gene Expression Data
Assay Details
Assay
Reference: J:249381 Yang AW, et al., Deletion of Inpp5a causes ataxia and cerebellar degeneration in mice. Neurogenetics. 2015 Oct;16(4):277-85
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7616312
Gene symbol: Inpp5a
Gene name: inositol polyphosphate-5-phosphatase A
Antibody: anti-INPP5A
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1C +/+: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Purkinje cell Present 1C +/+ Expression restricted to Purkinje cells.
TS28: cerebellum molecular layer Strong Regionally restricted 1C +/+ Highest expression in dendritic arbor. Less expression in soma.

Specimen 1C -/-: postnatal adult; \Inpp5aGt(OST50073)Lex/\Inpp5aGt(OST50073)Lex (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent 1C -/-


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory