About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:213418 Li D, et al., Formation of proximal and anterior limb skeleton requires early function of Irx3 and Irx5 and is negatively regulated by Shh signaling. Dev Cell. 2014 Apr 28;29(2):233-40
Assay type: RNA in situ
MGI Accession ID: MGI:7615130
Gene symbol: Pax9
Gene name: paired box 9
Probe: Pax9 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 1Q: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 1Q Expressed in the anterior region.
Specimen 1R: embryonic day 11.5; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 1R Similar as in the control, expressed in the anterior region.
Specimen 1S: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted 1S Expressed in the anterior region.
Specimen 1T: embryonic day 11.5; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Absent 1T
Specimen 3M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 3M Expressed in the anterior region.
Specimen 3N: embryonic day 11.5; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 3N Expressed in the anterior region, similar as in the control.
Specimen 3O: embryonic day 11.5; Kif7tm1.2Hui/Kif7tm1.2Hui (more )
Structure Level Pattern Image Note
TS19: forelimb bud Present Regionally restricted 3O Reduced expression in the anterior region compared with the control.
Specimen 3P: embryonic day 11.5; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui, Kif7tm1.2Hui/Kif7tm1.2Hui (more )
Structure Level Pattern Image Note
TS19: forelimb bud Absent 3P
Specimen 4Q: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindlimb Present Regionally restricted 4Q Expressed in the anterior region.
Specimen 4R: embryonic day 12.5; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui (more )
Structure Level Pattern Image Note
TS20: hindlimb Ambiguous 4R Trace or no expression in the anterior region.
Specimen 4S: embryonic day 12.5; Irx3tm3.1Hui/Irx3tm3.1Hui, Irx5tm3Hui/Irx5tm3Hui, Shhtm1Chg/Shh+ (more )
Structure Level Pattern Image Note
TS20: hindlimb Present Regionally restricted 4S Expression in the anterior region was rescued.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory