About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:286599 Song NN, et al., Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199
Assay type: RNA in situ
MGI Accession ID: MGI:7608306
Gene symbol: Phox2a
Gene name: paired-like homeobox 2a
Results
Specimen 2C Phox2a Control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 2C Phox2a Control Expression in dorsal rhombomere 1.
Specimen 2C Phox2a Zc4h2 KO: embryonic day 10.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 2C Phox2a KO Expression not changed compared to control.
Specimen 2D Phox2a Control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 2D Phox2a Control
Specimen 2D Phox2a Zc4h2 KO: embryonic day 12.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS20: pons Weak 2D Phox2a KO Expression slightly reduced compared to control.
Specimen 2E Phox2a Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 2E Phox2a Control
Specimen 2E Phox2a Zc4h2 KO: embryonic day 16.5; Zc4h2em1.1Yqd/Zc4h2em1.1Yqd (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Absent 2E Phox2a KO Expression not observed.
Specimen 3C Phox2a: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 3C Phox2a
Specimen 3E Phox2a Control: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 3E Phox2a Control Expression in dorsal rhombomere 1.
Specimen 3E Phox2a Rnf220 KO: embryonic day 10.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS17: rhombomere 1 Present Regionally restricted 3E Phox2a KO Expression similar to that of control.
Specimen 3F Phox2a Control: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pons Present Regionally restricted 3F Phox2a Control
Specimen 3F Phox2a Rnf220 IO: embryonic day 12.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS20: pons Weak 3F Phox2a KO Expression reduced compared to control.
Specimen 3H Phox2a Control: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Present 3H Phox2a Control
Specimen 3H Phox2a Rnf220 KO: embryonic day 16.5; Rnf220em1.1Kust/Rnf220em1.1Kust (more )
Structure Level Pattern Image Note
TS24: locus coeruleus Trace 3H Phox2a KO Expression hardly detected in locus coeruleus region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory