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Gene Expression Data
Assay Details
Assay
Reference: J:293624 Lee S, et al., Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development. 2020 Apr 30;147(21):dev187369
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7607132
Gene symbol: Axin2
Gene name: axin 2
Reporter: lacZ
Antibody: anti-B-galactosidase (ab9361)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6B Esrp1+/+;Axin2LacZ E10.5: embryonic day 10.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS17: latero-nasal process Present 6B top left
TS17: medial-nasal process ectoderm Present 6B top left
TS17: medial-nasal process mesenchyme Present 6B top left
Specimen 6B Esrp1-/-;Axin2LacZ E10.5: embryonic day 10.5; Axin2tm1Wbm/Axin2+, Esrp1tm1.2Rpc/Esrp1tm1.2Rpc (more )
Structure Level Pattern Image Note
TS17: latero-nasal process Present 6B top right The fluorescence intensity was not significantly changed from control.
TS17: medial-nasal process ectoderm Weak 6B top right
TS17: medial-nasal process mesenchyme Weak 6B top right
Specimen 6B Esrp1+/+;Axin2LacZ E11.5: embryonic day 11.5; Axin2tm1Wbm/Axin2+ (more )
Structure Level Pattern Image Note
TS19: maxillary process Present 6B lower left
Specimen 6B Esrp1-/-;Axin2LacZ E11.5: embryonic day 11.5; Axin2tm1Wbm/Axin2+, Esrp1tm1.2Rpc/Esrp1tm1.2Rpc (more )
Structure Level Pattern Image Note
TS19: maxillary process Weak 6B lower right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/30/2025
MGI 6.24 		The Jackson Laboratory