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Gene Expression Data
Assay Details
Assay
Reference: J:150356 Jacobs FM, et al., Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neurons. Development. 2009 Jul;136(14):2363-73
Assay type: RNA in situ
MGI Accession ID: MGI:7596530
Gene symbol: Slc6a3
Gene name: solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
Probe: Dat cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 8C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 8C Expressed in the lateral population of the mesodiencephalic dopamine neuronal area in rostral sections.

Specimen 8C': embryonic day 14.5; Dlk1tm1Hsul/Dlk1tm1Hsul (more )
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 8C' Expressed in the lateral population of the mesodiencephalic dopamine neuronal area in rostral sections. Also ectopically expressed in the medial region.

Specimen 8G: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 8G No expression in the caudal region. Expressed in the lateral population of the mesodiencephalic dopamine neuronal area in rostral sections.

Specimen 8G': embryonic day 14.5; Dlk1tm1Hsul/Dlk1tm1Hsul (more )
Structure Level Pattern Image Note
TS22: midbrain Present Regionally restricted 8G' Ectopic expression in the mutant was seen.

Specimen 8I: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: thalamus Absent 8I

Specimen 8J: embryonic day 14.5; Dlk1tm1Hsul/Dlk1tm1Hsul (more )
Structure Level Pattern Image Note
TS22: thalamus Present 8J Ectopic expression was seen in the mutant.

Specimen 8M: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindbrain Absent 8M

Specimen 8N: embryonic day 14.5; Dlk1tm1Hsul/Dlk1tm1Hsul (more )
Structure Level Pattern Image Note
TS22: hindbrain Present Regionally restricted 8N Ectopic expression was seen in the mutant. Expressed in tissues positive for Nr4a2/Nurr1 and Dlk1.

Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: substantia nigra Present
TS26: ventral tegmental area Present

Specimen not shown: embryonic day 18.5; Dlk1tm1Hsul/Dlk1tm1Hsul (more )
Structure Level Pattern Image Note
TS26: substantia nigra Present Similar as in the wild-type.
TS26: ventral tegmental area Present Similar as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory