Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:317363 Ruiz-Serrano A, et al., OTUB1 regulates lung development, adult lung tissue homeostasis, and respiratory control. FASEB J. 2021 Dec;35(12):e22039
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7596439
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved caspase-3 (Asp175) (5A1E; #9664)
Detection system:	Secondary antibody coupled to horseradish peroxidase

Results

4E Wt ©

Specimen 4E Wt: embryonic day 18.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: lung	Weak		4E Wt	Very low overall levels of expression.

4E Otub2+/- ©

Specimen 4E Otub1+/-: embryonic day 18.5; Otub1^{tm1b(EUCOMM)Hmgu}/Otub1⁺ (more

)

Structure	Level	Pattern	Image	Note
TS26: lung	Ambiguous		4E Otub2+/-	Expression significantly decreased compared to wild type.

4E Otub1-/- ©

Specimen 4E Otub1-/-: embryonic day 18.5; Otub1^{tm1b(EUCOMM)Hmgu}/Otub1^{tm1b(EUCOMM)Hmgu} (more

)

Structure	Level	Pattern	Image	Note
TS26: lung	Weak		4E Otub1-/-	Expression comparable to that of wild type.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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